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2-(Aminomethyl)-1-Boc-piperidine

Basic information Safety Supplier Related

2-(Aminomethyl)-1-Boc-piperidine Basic information

Product Name:
2-(Aminomethyl)-1-Boc-piperidine
Synonyms:
  • (1-AMINOMETHYL-PROPYL)-METHYL-CARBAMIC ACID TERT-BUTYL ESTER
  • 1-BOC-2-AMINOMETHYL-PIPERIDINE
  • 2-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • 2-(AMINOMETHYL)-1-BOC-PIPERIDINE
  • 2-(AMINOMETHYL)-1-N-BOC-PIPERIDINE
  • tert-butyl 2-(aminomethyl)piperidine-1-carboxylate
  • 1-N-BOC-2-(AMINOMETHYL)PIPERIDINE
  • 1-PIPERIDINECARBOXYLIC ACID, 2-(AMINOMETHYL)-, 1,1-DIMETHYLETHYL ESTER
CAS:
370069-31-1
MF:
C11H22N2O2
MW:
214.3
Product Categories:
  • pharmacetical
  • Aminomethyl's
  • Pyrans, Piperidines &Piperazines
  • Piperidine
  • API intermediates
  • Pyrans, Piperidines & Piperazines
  • Building Blocks
  • Heterocyclic Building Blocks
  • Piperidines
Mol File:
370069-31-1.mol
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2-(Aminomethyl)-1-Boc-piperidine Chemical Properties

Boiling point:
299.4±13.0 °C(Predicted)
Density 
1.0124 g/mL at 25 °C
refractive index 
n20/D 1.4745
Flash point:
110 °C
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
Soluble in DMSO.
pka
10.32±0.29(Predicted)
CAS DataBase Reference
370069-31-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn,N
Risk Statements 
22-36/37/38-50
Safety Statements 
26-61
RIDADR 
UN 3082 9/PG 3
WGK Germany 
3
HazardClass 
IRRITANT
HazardClass 
9
HS Code 
29242990
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2-(Aminomethyl)-1-Boc-piperidine Usage And Synthesis

Chemical Properties

White powder

Uses

Reactant for synthesis of:
TRPV1 antagonists
CHK1 inhibitors
p38a MAP kinase inhibitors
Carbamoylphosphonates
Macrolactams via carbonylation/intramolecular amidation
Intramolecular transamidation

Reactions

2-(Aminomethyl)-1-Boc-piperidine, also known as Tert-butyl 2-(aminomethyl)piperidine-1-carboxylate, is an important organic reagent that can be used as a building block for the synthesis of many organic compounds, such as tert-butyl 2 - ((2, 6 - dimethyl-phenyl amide) methyl) piperidine -1 - carboxylic esters which can be used for preparing medicines in the fields of local anaesthesia or analgesia.

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