CALCITONIN, HUMAN Chemical Properties

Boiling point:

3061.8±65.0 °C(Predicted)

Density 

1.326±0.06 g/cm3(Predicted)

RTECS 

XP3560000

storage temp. 

−20°C

solubility 

Soluble in DMSO

form 

powder

Water Solubility 

Soluble to 2 mg/ml in water

Merck 

13,1642

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

CALCITONIN, HUMAN Usage And Synthesis

Uses

Regulator (calcium).

Uses

Decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes. A carrier peptide that can be used to internalize fusion proteins

Uses

Calcitonin human has been used to study its ability to stimulate cAMP production post transfection in mammalian cell by activating human CALCRL (calcitonin receptor like receptor gene)- receptor activity-modifying protein 1 (RAMP1) and CTR (calcitonin receptor).

brand name

Calcimar (Rhone- Poulenc Rorer);.

Biochem/physiol Actions

Calcitonin, also referred to as thyrocalcitonin, is a 32 amino acid peptide hormone, which is present abundantly in seminal plasma compared to serum. It acts as a first messenger and hence regulates the the production of cAMP as well as mammalian sperm function. It also facilitates the regulation of different isoforms of adenylyl cyclase.

storage

Store at -20°C

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