PROPARGYLAMINE Chemical Properties

Boiling point:

84 °C

Density 

0.86

refractive index 

n20/D 1.449(lit.)

Flash point:

39 °F

storage temp. 

2-8°C

solubility 

soluble in Chloroform, Ethyl Acetate

form 

Liquid

pka

7.89±0.29(Predicted)

color 

Clear colorless to yellow

Water Solubility 

miscible

Sensitive 

Air Sensitive

BRN 

773681

Dielectric constant

6.6500000000000004

CAS DataBase Reference

2450-71-7(CAS DataBase Reference)

NIST Chemistry Reference

Propargylamine(2450-71-7)

EPA Substance Registry System

2-Propyn-1-amine (2450-71-7)

Safety Information

Hazard Codes 

F,T

Risk Statements 

11-22-24-34

Safety Statements 

16-26-33-36/37/39-45-28A

RIDADR 

UN 1992 3/PG 2

WGK Germany 

3

RTECS 

UK5250000

F 

3-8-10-34

TSCA 

Yes

HazardClass 

3.1

PackingGroup 

II

HS Code 

29211990

MSDS

• Language:English Provider:2-Propyn-1-amine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

PROPARGYLAMINE Usage And Synthesis

Chemical Properties

clear colorless to yellow liquid

Uses

A useful intermediates in the preparation of drugs or pesticides.

Uses

Propargylamine is used in the synthesis of a chiral, a fluorescent macrocycle by 1,3-dipolar cycloaddition of propargyl amides of carbohydrate-linked amino acids and 9,10-bis(azidomethyl)anthracene. It acts as an intermediate in the production of drugs.

Uses

Synthesis of a chiral, fluorescent macrocycle by 1,3-dipolar cycloaddition of propargyl amides of carbohydrate-linked amino acids and 9,10-bis(azidomethyl)anthracene.

Enzyme inhibitor

This alkynyl amine HCCCH2–NH2 (FWfree-base = 55.08 g/mol), also known as propargylamine and 3-amino-1-propyne, is a toxic liquid that boils at 83°C. The water-soluble hydrochloride melts at 179-182°C. Target(s): aldehyde dehydrogenase; diamine oxidase, or amine oxidase [copper-containing]; glycine cleavage complex, or glycine synthase; and monoamine oxidase, or amine oxidase [flavin-containing].

PROPARGYLAMINE(2450-71-7)Related Product Information

• Bis(2-ethylhexyl)amine
• FLUMIOXAZIN
• Dibenzylamine
• :(S)-2-Methyl-3-(2-propynyl)-4-oxocyclopent-2-enyl-(lR)-cis,trans-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate
• 3-Bromopropyne
• Propyne
• Propiolic Acid
• Diisopropylammonium dichloroacetate
• Triethanolamine
• Isopropylamine
• Triallylamine
• Propyzamide
• Malonamide
• Pomalidomide
• Benzylamine
• (-)-2-[METHYLAMINO]-1-PHENYLPROPANE
• Propargyl alcohol
• PROPYNYLAMINE HYDROCHLORIDE,2-PROPYNYLAMINE HYDROCHLORIDE,2-PROPYNYLAMINE HCL,2-Propynylamine hydrochloride, 3-Amino-1-propyne hydrochloride