6-PHOSPHOGLUCONIC DEHYDROGENASE Chemical Properties

storage temp. 

2-8°C

form 

lyophilized powder

biological source

yeast

Specific Activity

≥3.0units/mg solid

EPA Substance Registry System

Dehydrogenase, phosphogluconate (decarboxylating) (9073-95-4)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

F 

3-10

MSDS

• Language:English Provider:SigmaAldrich

6-PHOSPHOGLUCONIC DEHYDROGENASE Usage And Synthesis

Uses

6-Phosphogluconic Dehydrogenase from yeast has been used in hexokinase (HK) and xylose reductase (XR) activities in cell lysate.

General Description

6-Phosphogluconic Dehydrogenase from yeast comprises of a NADP⁺ binding domain, α helical hydrophobic interaction domain and a C-terminal domain. It exists as dimer and the C-terminal region is crucial for the substrate binding and release.

Biochem/physiol Actions

Enzyme activity is determined by measuring the reduction of NAD+ or NADP+. High levels of NADPH are believed to inhibit the enzyme, while 6-phosphogluconate acts to activate the enzyme.

6-PHOSPHOGLUCONIC DEHYDROGENASE(9073-95-4)Related Product Information

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