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Methabenzthiazuron

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Methabenzthiazuron Basic information

Product Name:
Methabenzthiazuron
Synonyms:
  • 1-(2-benzothiazolyl)-1,3-dimethyl-ure
  • 1,3-dimethyl-3-(2-benzthiazolyl)-harnstoff
  • bay74283
  • bayer5633
  • metabenzthiazuron
  • methbenzthiazuron
  • n-methyl-n’-methyl-n’-(2-benzothiazolyl)urea
  • preparation5633
CAS:
18691-97-9
MF:
C10H11N3OS
MW:
221.28
EINECS:
242-505-0
Product Categories:
  • BENZOTHIAZOLE
Mol File:
18691-97-9.mol
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Methabenzthiazuron Chemical Properties

Melting point:
119-120.5°
Density 
1.2527 (rough estimate)
refractive index 
1.6740 (estimate)
Flash point:
11 °C
storage temp. 
APPROX 4°C
solubility 
DMSO, Methanol (Sparingly)
pka
12.83±0.46(Predicted)
color 
Off-White to Pale Beige
Water Solubility 
59mg/L(20 ºC)
Merck 
14,5939
BRN 
196633
EPA Substance Registry System
Methabenzthiazuron (18691-97-9)
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Safety Information

Hazard Codes 
N,T,F
Risk Statements 
50/53-39/23/24/25-23/24/25-11
Safety Statements 
60-61-45-16-7
RIDADR 
UN 3077 9/PG 3
WGK Germany 
2
RTECS 
YR8980000
HazardClass 
9
PackingGroup 
III
HS Code 
29342000
Toxicity
LD50 in mice (mg/kg): >1000 orally; in male, female rats (mg/kg): >2500, >2500 orally; 540, 315 i.p. (Kimmerle, Lser)
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Methabenzthiazuron Usage And Synthesis

Chemical Properties

White crystalline solid; melts at 120°C(248°F); insoluble in water [~59 ppm at20°C (68°F)], soluble in organic solvents.

Uses

Methabenzthiazuron is a benzothiazole and urea based herbicide used to control a spectrum of broad-leaved weeds and grasses crops. Methabenzthiazuron works via the inhibition of photosynthetic electron transport chain.

Uses

Methabenzthiazuron is a benzothiazole and urea based herbicide used to control a spectrum of broad-leaved weeds and grasses crops. Methabenzthiazuron works via the inhibition of photosynthetic electro n transport chain.

Uses

Selective herbicide.

Definition

ChEBI: Methabenzthiazuron is a member of benzothiazoles.

Health Hazard

Gupta and Singh (1985) investigated thetoxicity of tribunil in calves. Animals treatedwith 500 mg/kg orally developed toxicityin 36–48 hours. The symptoms includedincrease in body temperature, depression,and a progressive decrease in respiration rateand pulse rate. Necropsy findings in animalsthat died showed congestion of the lungs.Other organs affected were liver, kidney,urinary bladder, spleen, heart, and brain.A 75-mg/kg dose produced toxicity after2–3 weeks.

Metabolic pathway

When methabenzthiazuron is presowing applied to the soil of pea fields, three degradation products are detected as (2-benzothiazoyl)urea, 2- (methylamino)benzothiazole and 2- aminobenzothiazole. The latter two amines represent a majority of the soil bound residues.

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