N-Cbz-L-glutamic acid Chemical Properties

Melting point:

115-117 °C(lit.)

alpha 

-7.4 º (c=10, CH3COOH 22 ºC)

Boiling point:

423.93°C (rough estimate)

Density 

1.2801 (rough estimate)

refractive index 

-7.5 ° (C=8, AcOH)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMF, Methanol

form 

Solid

pka

3.81±0.10(Predicted)

color 

Off-White

optical activity

[α]22/D 7.4°, c = 10 in acetic acid

BRN 

2061272

InChI

InChI=1S/C13H15NO6/c15-11(16)7-6-10(12(17)18)14-13(19)20-8-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,14,19)(H,15,16)(H,17,18)/t10-/m0/s1

InChIKey

PVFCXMDXBIEMQG-JTQLQIEISA-N

SMILES

C(O)(=O)[C@H](CCC(O)=O)NC(OCC1=CC=CC=C1)=O

CAS DataBase Reference

1155-62-0(CAS DataBase Reference)

EPA Substance Registry System

L-Glutamic acid, N-[(phenylmethoxy)carbonyl]- (1155-62-0)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38

Safety Statements 

22-24/25-36-26

WGK Germany 

3

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29242990

MSDS

• Language:English Provider:N-Benzyloxycarbonyl-L-glutamic acid
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

N-Cbz-L-glutamic acid Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

Used for the synthesis of carboxyalkyl peptides as inhibitors of angiotensin-converting enzyme of human blood serum.

Uses

N-Cbz-L-glutamic acid is used for the synthesis.

reaction suitability

reaction type: solution phase peptide synthesis

N-Cbz-L-glutamic acid(1155-62-0)Related Product Information

• Polyglutamic acid
• L-Pyroglutamic acid
• GLDH
• Trimethoprim
• Folic acid
• L-(+)Sodium glutamate
• Benzyloxyacetyl chloride
• Ethyl 2-(Chlorosulfonyl)acetate
• L-Glutamic acid
• 1,1'-Carbonyldiimidazole
• N-Benzyloxycarbonyl-L-proline
• N-Cbz-L-Tryptophan
• N-Cbz-L-Threonine
• N-Carbobenzyloxyglycine
• N-Cbz-L-Phenylalanine
• N-Cbz-L-Leucine
• Citric acid
• N-Cbz-L-Aspartic acid 4-benzyl ester