5-Methylindole Chemical Properties

Melting point:

60-62 °C (lit.)

Boiling point:

100°C/3mm

Density 

1.0202

refractive index 

1.6070 (estimate)

Flash point:

100°C/3mm

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

17.17±0.30(Predicted)

form 

Crystalline Solid

color 

White to slightly beige

Water Solubility 

Insoluble in water.

Sensitive 

Light Sensitive

BRN 

2228

LogP

2.680

CAS DataBase Reference

614-96-0(CAS DataBase Reference)

NIST Chemistry Reference

1H-Indole, 5-methyl-(614-96-0)

EPA Substance Registry System

5-Methylindole (614-96-0)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-24/25

RIDADR 

UN3335

WGK Germany 

3

Hazard Note 

Light Sensitive/Keep Cold

HS Code 

29339900

MSDS

• Language:English Provider:5-methyl-1H-indole
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

5-Methylindole Usage And Synthesis

Chemical Properties

white to slightly beige crystalline solid

Uses

5-Methylindole is used as reactant for preparation of pharmaceutically active 2-oxo-1-pyrrolidine analogues, potential anticancer immunomodulators, IL2-inducible T-cell kinase (ITK) inhibitors and CRTh2 antagonists.

Uses

5-Methylindole is used in the synthesis of novel protein kinase inhibitors.

Synthesis Reference(s)

Synthesis, p. 1036, 1982 DOI: 10.1055/s-1982-30054

General Description

The binding of 5-methylindole (inducer) to the Escherichia coli trp repressor has been studied. The mass analyzed threshold ionization spectra of jetcooled 5-methylindole (5MI) has also been studied.

5-Methylindole(614-96-0)Related Product Information

• Thiophanate-methyl
• Bensulfuron methyl
• Kresoxim-methyl
• Methyl acrylate
• Methylparaben
• 5-Methyl-1H-imidazole-4-carbaldehyde
• Methyl
• 2,5-Dimethylindole
• 5-METHYLINDOLE-2-CARBOXYLIC ACID
• 5-METHYL-N,N-DIMETHYLTRYPTAMINE
• 5-Ethylindole
• N-Ethyl-3-carbazolecarboxaldehyde
• Indole-5-carboxylic acid
• 2-Methylindole
• 5-Cyanoindole
• 5-METHYLGRAMINE
• 5-Methyltryptamine hydrochloride
• Parathion-methyl