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3,5-Bis(trifluoromethyl)benzyl alcohol

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3,5-Bis(trifluoromethyl)benzyl alcohol Basic information

Product Name:
3,5-Bis(trifluoromethyl)benzyl alcohol
Synonyms:
  • RARECHEM AL BD 0207
  • 3,5-BIS(TRIFLUOROMETHYL)BENZYL ALCOHOL
  • (3,5-BIS-TRIFLUOROMETHYL-PHENYL)-METHANOL
  • [3,5-DI(TRIFLUOROMETHYL)PHENYL]METHANOL
  • 3,5-DI(TRIFLUORO METHYL)BENZYLALCOHOL
  • TIMTEC-BB SBB000837
  • 3,5-Bis(trifluromethyl)benzyl alcohol, 98%
  • 3,5-Bis(trifluoromethyl)benzyl alcohol 98%
CAS:
32707-89-4
MF:
C9H6F6O
MW:
244.13
EINECS:
251-168-9
Product Categories:
  • Fluorine series
  • Building Blocks
  • C9 to C10
  • Chemical Synthesis
  • Organic Building Blocks
  • Oxygen Compounds
  • Alcohols
  • C9 to C30
  • Oxygen Compounds
  • Benzhydrols, Benzyl & Special Alcohols
  • Alcohol
  • Miscellaneous
  • Fluorides
Mol File:
32707-89-4.mol
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3,5-Bis(trifluoromethyl)benzyl alcohol Chemical Properties

Melting point:
53-56 °C(lit.)
Boiling point:
40°C 0,5mm
Density 
1.3954 (estimate)
Flash point:
208 °F
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystaline
pka
13.92±0.10(Predicted)
color 
White to Almost white
BRN 
2055358
InChI
InChI=1S/C9H6F6O/c10-8(11,12)6-1-5(4-16)2-7(3-6)9(13,14)15/h1-3,16H,4H2
InChIKey
BJTWPJOGDWRYDD-UHFFFAOYSA-N
SMILES
C1(CO)=CC(C(F)(F)F)=CC(C(F)(F)F)=C1
CAS DataBase Reference
32707-89-4(CAS DataBase Reference)
NIST Chemistry Reference
3,5-Bis(trifluoromethyl)benzyl alcohol(32707-89-4)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-36-37/39-36/37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29052900

MSDS

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3,5-Bis(trifluoromethyl)benzyl alcohol Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

3,5-bis(trifluoromethyl)benzylalcohol is also a very useful intermediate in the preparation of 3,5-bis(trifluoromethyl)halo-benzyls, for example 3,5-bis(trifluoromethyl)benzylbromide or benzylchloride.

Synthesis

A process for preparing 3,5-Bis(trifluoromethyl)benzyl alcohol by formylation in a solvent of an appropriate organo-magnesium derivative with solid paraformaldehyde and optionally its conversion into a 3,5-bis(trifluoromethyl)benzyl halide.

References

[1] Patent: EP1191012, 2002, A1. Location in patent: Page 5
[2] Patent: US2002/38055, 2002, A1

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