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N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine

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N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine Basic information

Product Name:
N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine
Synonyms:
  • SHIKAWA'S REAGENT
  • N,N-DIETHYL-1,1,2,3,3,3-HEXAFLUOROPROPYLAMINE
  • Ishikawa's Reagent, 1-(Diethylamino)-1,1,2,3,3,3-hexafluoropropane
  • N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine, 40% solution in THF
  • Ishikawa
  • Ishikawa's Reagent, technical, 90%
  • Ishikawa Reagent
  • MEC-81
CAS:
309-88-6
MF:
C7H11F6N
MW:
223.16
EINECS:
628-698-8
Product Categories:
  • Fluorinated Building Blocks
  • Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds
  • Fluorination
  • Halogenation
  • Synthetic Organic Chemistry
  • Chemical Synthesis
  • Fluorination Reagents
  • Synthetic Reagents
Mol File:
309-88-6.mol
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N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine Chemical Properties

Boiling point:
56-57 °C (lit.)
Density 
1.230 g/mL at 25 °C (lit.)
refractive index 
1.3460
Flash point:
56-57°C/58mm
storage temp. 
Flammables area
solubility 
soluble in Acetone,Ether
pka
1.50±0.70(Predicted)
form 
Liquid
color 
Clear colorless to yellow
Specific Gravity
1.230
Merck 
14,5108
CAS DataBase Reference
309-88-6(CAS DataBase Reference)
EPA Substance Registry System
N,N-Diethyl-2H-perfluoropropanamine (309-88-6)
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Safety Information

Hazard Codes 
C
Risk Statements 
10-34
Safety Statements 
16-26-36/37/39-45
RIDADR 
3267
WGK Germany 
3
Hazard Note 
Corrosive
HazardClass 
8
PackingGroup 
II
HS Code 
29211999

MSDS

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N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine Usage And Synthesis

Chemical Properties

Clear colorless to yellow liquid

Uses

Demonstrates utility in fluorination.7

Uses

Reactant for:

  • Friedel-Crafts type arylation of hydrofluorocarbons
  • Microbial hydroxylation of antibiotics
  • Electrochemical fluorination of trialkylamines and tetraalkylammonium salts
  • Fluorination of pyrethroides

Reactant for synthesis of:
  • γ-Hydroxy-α-fluoro-α-trifluoromethylcarboxamide
  • Florfenicol and thiamphenicol

Uses

Fluorinating agent.

General Description

GC analysis includes Et2NCF=CFCF3 (two isomers), both of which are active fluorinating agents.

N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamineSupplier

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