DMT-2μ-O-Me-rG(ib) amidite
DMT-2μ-O-Me-rG(ib) amidite Basic information
- Product Name:
- DMT-2μ-O-Me-rG(ib) amidite
- Synonyms:
-
- DMT-2μ-O-Me-rG(ib) amidite
- 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite
- Guanosine, 5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-(2-Methoxyethyl)-N-(2-Methyl-1-oxopropyl)-, 3'-[2-cyanoethyl bis(1-Methylethyl)phosphoraMidite]
- 2'-MOE-G(iBu)-3'-phosphoramidite
- 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
- 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-methylguanosine-3'-(2-cyanoethyl diisopropylphosphoramidite)
- 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite
- 2'-O-MOE-G(iBu)-CE Phosphoramidite
- CAS:
- 251647-55-9
- MF:
- C47H60N7O10P
- MW:
- 913.99
- Product Categories:
-
- RNA Amidites
- Sigma-Proligo
- 2-Methyl RNA STD Amidites
- Amidite
- Mol File:
- 251647-55-9.mol
DMT-2μ-O-Me-rG(ib) amidite Chemical Properties
- storage temp.
- 4°C, protect from light
- solubility
- DMSO : 250 mg/mL (273.53 mM; Need ultrasonic)
- form
- Powder
- pka
- 9.16±0.20(Predicted)
- color
- White to Off-white
- InChI
- InChI=1/C47H60N7O10P/c1-30(2)43(55)51-46-50-42-39(44(56)52-46)49-29-53(42)45-41(60-27-26-57-7)40(64-65(62-25-13-24-48)54(31(3)4)32(5)6)38(63-45)28-61-47(33-14-11-10-12-15-33,34-16-20-36(58-8)21-17-34)35-18-22-37(59-9)23-19-35/h10-12,14-23,29-32,38,40-41,45H,13,25-28H2,1-9H3,(H2,50,51,52,55,56)/t38-,40-,41-,45-,65?/s3
- InChIKey
- LADCDGNEBIQAAU-KEFUZROQNA-N
- SMILES
- O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](OCCOC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,44,50,r|
DMT-2μ-O-Me-rG(ib) amidite Usage And Synthesis
Description
Nucleoside phosphoramidites are used in the synthesis of oligonucleotides. Using a chemical approach allows quick and inexpensive access to custom-made oligonucleotides of the desired sequence. Enzymatic synthesis proceeds in a 5’ to 3’ direction, however the chemical synthesis is usually performed in the opposite direction. 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite, also known as DMT-2μ-O-Me-rG(ib) amidite, is a modified guanosine with a 2’-O-(2-methoxyethyl) group, these have been used in the synthesis of oligonucleotides as antisense drugs.
Uses
5''-O-DMT-N2-isobutyryl-2''-O-(2-methoxyethyl)-guanosine 3''-CE phosphoramidite (CAS# 251647-55-9) is a nucleotide, and a derivative of guanosine, and is used in the stereochemical sythesis of phosphorothioate oligonucleotides.
storage
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
DMT-2μ-O-Me-rG(ib) amiditeSupplier
- Tel
- 17333066501
- shengwen.fang@huanaok.com.cn
- Tel
- 0371-85513397
- info@granlen.com
- Tel
- 13335632219
- 3152731197@qq.com
- Tel
- 15555170917
- sales@stongbio.com
- Tel
- 0512-52112288 13752065514
- jianwei@chemyouth.com
DMT-2μ-O-Me-rG(ib) amidite(251647-55-9)Related Product Information
- 2'-O-Methylcytidine
- 2’-O-Methyl-rA(N-Bz)phosphoramidite
- DMT-2′Fluoro-dU Phosphoramidite
- 2'-O-MOE-A(Bz)-3'-phosphoramidite
- 2'-O-(2-Methoxyethyl)-5-methyluridine
- N-blocked-5'-O-DMT-2'-O-Me CED cytosine phosphoramidite
- N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite
- Dmt-2'-f-dc(ac) amidite
- 2'-O-Methyladenosine
- 2'-O-(2-Methoxyethyl)cytidine
- 2'-O-Methylguanosine
- 2'-O-(2-Methoxyethyl)uridine
- DMT-2'-O-MOE-rU Phosphoramidite
- 2'-O-MOE-ADENOSINE
- 2'-OMe-ibu-G Phosphoramidite
- 2'-O-(2-Methoxyethyl)guanosine