4-Bromofluorobenzene Chemical Properties

Melting point:

−16 °C(lit.)

Boiling point:

150 °C(lit.)

Density 

1.593 g/mL at 25 °C(lit.)

vapor pressure 

4.99hPa at 25℃

refractive index 

n20/D 1.527(lit.)

Flash point:

140 °F

storage temp. 

2-8°C

solubility 

0.136g/l

form 

Liquid

color 

Clear colorless

Water Solubility 

Soluble in water(0.14g/L).

BRN 

774102

LogP

3.018 at 25℃

CAS DataBase Reference

460-00-4(CAS DataBase Reference)

NIST Chemistry Reference

p-Bromofluorobenzene(460-00-4)

EPA Substance Registry System

p-Bromofluorobenzene (460-00-4)

Safety Information

Hazard Codes 

Xi,F,Xn,T

Risk Statements 

10-36/37/38-20-39/23/24/25-23/24/25-11-20/21/22

Safety Statements 

26-36-37/39-16-45-36/37-7

RIDADR 

UN 1993 3/PG 3

WGK Germany 

1

RTECS 

CY9033750

Hazard Note 

Flammable/Irritant

TSCA 

Yes

HazardClass 

3

PackingGroup 

III

HS Code 

29036990

MSDS

• Language:English Provider:1-Bromo-4-fluorobenzene
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

4-Bromofluorobenzene Usage And Synthesis

Chemical Properties

clear colorless liquid

Uses

4-Bromofluorobenzene is a dihalogenated benzene used in the preparation of pharmaceutical compounds such as atypical antipsychotic agents.

Uses

1-Bromo-4-fluorobenzene is used as an intermediate in the synthesis of atypical antipsychotic agents.

Uses

4-Bromofluorobenzene can act like a surrogate standard for the:
determination of toxicity of diesel and water accommodated diesel fraction (WAF), towards microalgal species like Pseudokirchneriella subcapitata and Chlorella sp.MM3, using gas chromatography coupled with mass spectrometry (GC-MS).
determination of the chemicals like benzene, toluene, ethylbenzene and xylene (BTEX) and their stable carbon isotopic values, in gasoline contaminated ground-water, using gas chromatography coupled with mass spectrometry (GC-MS).

Definition

ChEBI: 1-bromo-4-fluorobenzene is a member of the class of bromobenzenes that is bromobenzene carrying a fluoro atom at position 4. It is a member of bromobenzenes and a member of monofluorobenzenes.

General Description

Colorless liquid.

Air & Water Reactions

Highly flammable. Insoluble in water.

Reactivity Profile

Simple aromatic halogenated organic compounds, such as 4-Bromofluorobenzene, are very unreactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group may be incompatible with strong oxidizing and reducing agents. Also, they may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

Health Hazard

ACUTE/CHRONIC HAZARDS: Irritant.

Flammability and Explosibility

Flammable

4-Bromofluorobenzene(460-00-4)Related Product Information

• Transfluthrin
• Florfenicol
• 3-Fluorobenzyl bromide
• 4-Fluoroanisole
• 1,2-Difluorobenzene
• 4-Fluorobenzaldehyde
• Fluorobenzene
• 4-Fluorobenzoic acid
• 1-Bromo-4-iodobenzene
• 4-Fluoronitrobenzene
• 4-Fluorophenoxyacetic acid
• Methyl 4-fluorobenzoate
• Ethyl 4-fluorobenzoate
• 4-Fluorobenzonitrile
• 4-Fluorobenzyl chloride
• 4-Fluorophenylacetic acid
• FENFLURAMINE
• 1-Bromo-2,4-difluorobenzene