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4-(Trifluoromethoxy)phenylmagnesium bromide

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4-(Trifluoromethoxy)phenylmagnesium bromide Basic information

Product Name:
4-(Trifluoromethoxy)phenylmagnesium bromide
Synonyms:
  • 4-(Trifluoromethoxy)phenylmagnesium bromide
  • (4-(Trifluoromethoxy)phenyl)magnesium bromide, 0.50 M in THF
  • (4-(Trifluoromethoxy)phenyl)magnesium bromide, 0.50 M in 2-MeTHF
  • 4-(Trifluoromethoxy)phenylmagnesium bromide solution
  • 4-(Trifluoromethoxy)phenylmagnesium bromide solution 0.5 M in THF
  • Magnesium, bromo[4-(trifluoromethoxy)phenyl]-
  • 4-(Trifluoromethoxy)phenylmagnesium bromide 0.5M in 2-MeTHF
CAS:
169222-42-8
MF:
C7H4BrF3MgO
MW:
265.3102696
Product Categories:
  • Grignard Reagent
  • Aryl
  • Grignard Reagents
  • Organometallic Reagents
Mol File:
169222-42-8.mol
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4-(Trifluoromethoxy)phenylmagnesium bromide Chemical Properties

Density 
0.975 g/mL at 25 °C
Flash point:
-30 °C
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Safety Information

Hazard Codes 
F,C
Risk Statements 
11-14-19-34-40-37
Safety Statements 
16-26-36/37/39-45
RIDADR 
UN 2924 3/PG 2
WGK Germany 
3
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4-(Trifluoromethoxy)phenylmagnesium bromide Usage And Synthesis

Uses

Reactant for:

  • Preparation of chromanol derivatives as novel class of CETP inhibitors for treatment of cardiovascular disease
  • Pd-catalyzed cross coupling
  • Preparation of indazole-pyridine derivatives as protein kinase B/Akt inhibitors with reduced hypotension, via Stille coupling, Mitsunobu reaction and copper-catalyzed aziridine ring-opening reaction

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