7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo-[1,2-a]quinoxaline maleate salt Chemical Properties

Melting point:

211 - 214°C

Boiling point:

419.3±45.0 °C(Predicted)

Density 

1.37±0.1 g/cm3(Predicted)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

7.27±0.42(Predicted)

form 

Solid

color 

White to Off-White

Stability:

Hygroscopic

7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo-[1,2-a]quinoxaline maleate salt Usage And Synthesis

Uses

CGS-12066A Maleate Salt displays 5-HT1 activity in mammals affecting mood involved with serotonin regulation.

Definition

ChEBI: 4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline is a pyrroloquinoxaline that is pyrrolo[1,2-a]quinoxaline bearing additional 4-methylpiperazin-1-yl and trifluoromethyl substituents at positions 4 and 7 respectively. A 5-hydroxytryptamine receptor 1B (5-HT1B) full agonist, 10-fold selective over 5-HT1A and 1000-fold selective over 5-HT2C receptors. Centrally active following systemic administration. It has a role as a serotonergic agonist. It is a N-arylpiperazine, an organofluorine compound and a pyrroloquinoxaline.

7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo-[1,2-a]quinoxaline maleate salt(109028-09-3)Related Product Information

• N,N-DIMETHYL-N'-PHENYLFORMAMIDINE
• 1-(2-AMINOPHENYL)PYRROLE
• A-AMINO-A-IMINOETHANE ACETATE
• 1-[4-(TRIFLUOROMETHYL)PHENYL]-1H-PYRROLE
• pyrrolo[1,2-a]quinoxaline
• Maleic acid
• 1-(4-METHYLPHENYL)-1 H-PYRROLE
• Ammonium hydrogen maleate
• (1-METHYL-1H-PYRROL-2-YL)METHYLAMINE
• 7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo-[1,2-a]quinoxaline maleate salt
• DIMETHYL-(1-METHYL-1H-PYRROL-2-YLMETHYL)-AMINE
• 2-Butene-1,4-diol
• METHYL-(1-METHYL-1H-PYRROL-2-YLMETHYL)-AMINE
• 5-METHYL-2-(1H-PYRROL-1-YL)ANILINE
• PIPERAZINE HEXAHYDRATE