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Isobutylamine

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Isobutylamine Basic information

Product Name:
Isobutylamine
Synonyms:
  • nsc8028
  • Valamine
  • ISOBUTYLAMINE
  • IBA
  • 1-AMINO-2-METHYLPROPANE
  • 2-Methylpropanamine
  • 2-METHYLPROPYLAMINE
  • 2-METHYL-1-PROPANAMINE
CAS:
78-81-9
MF:
C4H11N
MW:
73.14
EINECS:
201-145-4
Mol File:
78-81-9.mol
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Isobutylamine Chemical Properties

Melting point:
-85 °C (lit.)
Boiling point:
64-71 °C (lit.)
Density 
0.736 g/mL at 25 °C (lit.)
vapor pressure 
15.9kPa at 20℃
FEMA 
4239 | ISOBUTYLAMINE
refractive index 
n20/D 1.397(lit.)
Flash point:
15 °F
storage temp. 
Store below +30°C.
solubility 
1000g/l
form 
Liquid
pka
pK1:10.41(+1) (25°C)
color 
Clear colorless to slightly yellow
PH
12.2 (100g/l, H2O, 20℃)
Odor
Strong ammoniacal.
explosive limit
2-9%(V)
Odor Type
fishy
Odor Threshold
0.0015ppm
Water Solubility 
soluble
Merck 
14,5132
JECFA Number
1583
BRN 
385626
Dielectric constant
4.4(Ambient)
LogP
-0.3 at 25℃
CAS DataBase Reference
78-81-9(CAS DataBase Reference)
NIST Chemistry Reference
1-Propanamine, 2-methyl-(78-81-9)
EPA Substance Registry System
Isobutylamine (78-81-9)
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Safety Information

Hazard Codes 
F,C
Risk Statements 
11-22-35
Safety Statements 
26-36/37/39-45
RIDADR 
UN 1214 3/PG 2
WGK Germany 
1
RTECS 
NP9900000
10-23
TSCA 
Yes
HazardClass 
3
PackingGroup 
II
HS Code 
29211990
Hazardous Substances Data
78-81-9(Hazardous Substances Data)
Toxicity
LD50 (14 day) in male, female rats (mg/kg): 224.4, 231.8 orally (Cheever)

MSDS

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Isobutylamine Usage And Synthesis

Chemical Properties

Clear colorless to slightly yellow liquid

Chemical Properties

Colorless to yellow liquid; fishy cheesy aroma.

Chemical Properties

Isobutylamine is a flammable liquid, miscible with water, alcohol, and ether.

Chemical Properties

Butyl amines are highly flammable, colorless liquids (n-turns yellow on standing) with ammoniacal or fishlike odors. n-isomer:

Uses

Isobutylamine is used as pharmaceutical intermediate.

Uses

Isobutylamine may be used in the synthesis of N-i-butyl-9(Z),12(Z),15(Z)-octadecatrienamide by reacting with trilinolenin. It can also react with tropolone to form a hydrogen-bonded complex, iso-butyl-ammonium 7-oxo-cyclo-hepta-1,3,5-trien-1-olate. Fullerene (C60) can undergo oxyamination with isobutylamine to form polyamines.

Uses

Organic synthesis, insecticides.

Definition

ChEBI: An alkylamine having isobutyl as the alkyl group. It has been isolated from Sambucus nigra (Elderberry).

Production Methods

Isobutylamine is manufactured from isobutanol and ammonia or by the thermal decomposition of valine to isoleucine.

Aroma threshold values

High strength odor, fishy type; recommend smelling in a 0.10% solution or less.

General Description

A clear colorless liquid with a fishlike odor. Flash point 15°F. Less dense (6.1 lb / gal) than water. Vapors heavier than air. Produces toxic oxides of nitrogen during combustion.

Air & Water Reactions

Highly flammable. Soluble in water.

Reactivity Profile

Isobutylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Hazard

Flammable, dangerous fire risk. Strong irritant to skin and mucous membranes.

Health Hazard

Inhalation causes severe coughing and chest pain due to irritation of air passages; can cause lung edema. Compound is sympathomimetic and is also a cardiac depressant and convulsant; ingestion causes nausea and profuse salivation. Contact with eyes causes severe irritation and edema of the cornea. Contact with skin causes severe irritation.

Chemical Reactivity

Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Potential Exposure

Alert: (n-isomer): Possible risk of forming tumors, suspected of causing genetic defects, suspected reprotoxic hazard, Primary irritant (w/o allergic reaction), (sec-isomer): Drug. n-Butylamine is used in pharmaceuticals; dyestuffs, rubber, chemicals, emulsifying agents; photography, desizing agents for textiles; pesticides, and synthetic agents. sec-Butylamine is used as a fungistate. tert-Butylamine is used as a chemical intermediate in the production of tert-Butylaminoethyl methacrylate (a lube oil additive); as an intermediate in the production of rubber and in rust preventatives and emulsion deterrents in petroleum products. It is used in the manufacture of several drugs

Shipping

UN1125 n-Butylamine, Hazard Class: 3; Labels: 3—Flammable liquid, 8—Corrosive material. UN2014 Isobutylamine, Hazard Class: 3; Labels: 3—Flammable liquid, 8—Corrosive material

Incompatibilities

May form explosive mixture with air. May accumulate static electrical charges, and may causeignition of its vapors. n-Butylamine is a weak base; reacts with strong oxidizers and acids, causing fire and explosion hazard. Incompatible with organic anhydrides; isocyanates, vinyl acetate; acrylates, substituted allyls; alkylene oxides; epichlorohydrin, ketones, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. Attacks some metals in presence of moisture. The tert-isomer will attack some forms of plastics

Waste Disposal

Use a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner andscrubber. All federal, state, and local environmental regulations must be observed.

Isobutylamine Preparation Products And Raw materials

Raw materials

Preparation Products

IsobutylamineSupplier

Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Email
market03@meryer.com
Alfa Aesar
Tel
400-6106006
Email
saleschina@alfa-asia.com
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Email
Sales-CN@TCIchemicals.com
Energy Chemical
Tel
021-021-58432009 400-005-6266
Email
sales8178@energy-chemical.com
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Email
master@sjzsdyn.com