4-Bromobenzaldehyde Chemical Properties

Melting point:

55-58 °C(lit.)

Boiling point:

66-68°C 2mm

Density 

1.85 g/cm3

refractive index 

1.5727 (estimate)

Flash point:

228 °F

storage temp. 

Store below +30°C.

solubility 

Chloroform, Ethyl Acetate

form 

Crystalline Solid

color 

White

Water Solubility 

INSOLUBLE

Sensitive 

Air Sensitive

BRN 

507100

InChIKey

ZRYZBQLXDKPBDU-UHFFFAOYSA-N

LogP

2.75 at 25℃

CAS DataBase Reference

1122-91-4(CAS DataBase Reference)

NIST Chemistry Reference

Benzaldehyde, 4-bromo-(1122-91-4)

EPA Substance Registry System

Benzaldehyde, 4-bromo- (1122-91-4)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-36/37/38-43

Safety Statements 

26-36/37-36/37/39-22

RIDADR 

2811

WGK Germany 

2

RTECS 

CU4810000

Hazard Note 

Irritant/Harmful/Air Sensitive

TSCA 

Yes

HazardClass 

6.1(b)

PackingGroup 

III

HS Code 

29130000

MSDS

• Language:English Provider:4-Bromobenzaldehyde
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Bromobenzaldehyde Usage And Synthesis

Chemical Properties

white crystalline solid

Uses

4-Bromobenzaldehyde is widely utilized as an intermediate for the preparation of agrochemicals, pharmaceuticals and other organic compounds. It is used as a precursor and reacts with sulfamethoxazole to prepare Schiff?s base, 4-[(4-Bromo-benzylidene)-amino]-N-(5-methyl-isoxazol-3-yl)-benzene sulfonamide, which can be used for the photo stability of polyvinyl chloride (PVC). It plays an important role in palladium-catalyzed mono- and bis-arylation of 3,4-(ethylenedioxy)thiophenes. It is employed in a cross-coupling study with potassium vinyltrifluoroborate.

Uses

Employed in palladium-catalyzed mono- and bis-arylation of 3,4-(ethylenedioxy)thiophenes. Also used in a cross-coupling study with potassium vinyltrifluoroborate.

Reactions

4-Bromobenzaldehyde is widely utilized as an intermediate for preparing agrochemicals, pharmaceuticals, and other organic compounds. It is used as a precursor and reacts with sulfamethoxazole to prepare Schiff?s base, 4-[(4-Bromo-benzylidene)-amino]-N-(5-methyl-isoxazol-3-yl)-benzene sulfonamide, which can be used for the photostability of polyvinyl chloride (PVC). It plays a vital role in palladium-catalyzed mono- and bis-arylation of 3,4-(ethylenedioxy)thiophenes. It is employed in a cross-coupling study with potassium vinyltrifluoroborate.

Synthesis Reference(s)

Journal of the American Chemical Society, 81, p. 4113, 1959 DOI: 10.1021/ja01524a080
Tetrahedron Letters, 21, p. 813, 1980 DOI: 10.1016/S0040-4039(00)71512-7

4-Bromobenzaldehyde(1122-91-4)Related Product Information

• Methyl 4-bromobenzoate
• 4-Bromobenzoic acid
• 4-Nitrobenzaldehyde
• Ethyl 4-bromophenylacetate
• 4-Bromoanisole
• 4-Bromopyrazole
• 2-(4-Bromophenyl)ethylamine
• 4-Bromobenzotrifluoride
• 4-Isopropylaniline
• 1-Bromo-4-iodobenzene
• 4-Bromophenylacetic acid
• 4-Chlorobenzylamine
• 4-Cyanobenzaldehyde
• 4-Chlorobenzaldehyde
• 4-BROMO-DL-PHENYLALANINE
• 4-Chlorobenzonitrile
• 4-BROMOBENZHYDROL
• 4-Bromobenzyl chloride