Vertine【alkaloid】 Chemical Properties

Melting point:

245-7°C

Boiling point:

655.4±55.0 °C(Predicted)

Density 

1.30±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml

form 

A crystalline solid

pka

8.27±0.20(Predicted)

Vertine【alkaloid】 Usage And Synthesis

Description

This alkaloid has been isolated from Decodon verticillatus L. and forms colourless crystals from a mixture of MeOH and CHCl3. It has [α]_D + 39° (c 0.95, CHCl3) and gives an ultraviolet spectrum with absorption maxima at 260 and 285 mJ.1. The acetyl derivative crystallizes from Et20 with m.p. 183-5°C; [α]_D - 92.7° (c 0.96, CHCl3). Catalytic hydrogenation yields Decamine (q.v.).

Definition

ChEBI: Cryogenine is a quinolizidine alkaloid isolated from the flowering plant Heimia salicifolia and exhibits anti-inflammatory properties. It has a role as an anti-inflammatory agent and a plant metabolite. It is a dimethoxybenzene, a member of phenols, a quinolizidine alkaloid and an enoate ester.

References

Ferris., 1. Org. Chern., 27, 2985 (1962)