2,5-Thiophenedicarboxylic acid Chemical Properties

Melting point:

>300 °C (lit.)

Boiling point:

272.46°C (rough estimate)

Density 

1.473 (estimate)

refractive index 

1.5500 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

solid

pka

2.76±0.10(Predicted)

color 

White to Light yellow

Water Solubility 

Very soluble in water.

BRN 

136781

CAS DataBase Reference

4282-31-9(CAS DataBase Reference)

EPA Substance Registry System

2,5-Thiophenedicarboxylic acid (4282-31-9)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

3

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29349990

MSDS

• Language:English Provider:Thiophene-2,5-dicarboxylic acid
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2,5-Thiophenedicarboxylic acid Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

2,5-Thiophenedicarboxylic acid may be used as a thiophene based linker in the preparation of magnesium coordination networks. It may also be used as a precursor in the synthesis of 2,5-bis-benzoxazoyl-thiophene (EBF).
It may be used in the synthesis of the following:

• new cobalt(II) thiophenedicarboxylate coordination polymer
• novel mesogenic thiophene based supramolecular liquid crystals
• two novel coordination polymers with the formula {[Ln₂(2,5-tdc)₃(dmso)₂]H₂O}_n (Ln = Tb(III) and Dy(III)), (2,5-tdc² = 2,5-thiophenedicarboxylate and dmso = dimethylsulfoxide)

Synthesis Reference(s)

Journal of the American Chemical Society, 72, p. 2109, 1950 DOI: 10.1021/ja01161a065

General Description

2,5-Thiophenedicarboxylic acid (2,5-TDCA, H₂TDC) is an important building block in the preparation of fluorescent brightening agent, fungicides and anti-cancer drug. It has been generated by chlorination of adipic acid using thionyl chloride. Due to its diverse coordination modes, it is an excellent choice as an aromatic linker to generate coordination networks. The enthalpies of combustion and sublimation of 2,5-thiophenedicarboxylic acid have been evaluated by rotary-bomb combustion calorimetry.

2,5-Thiophenedicarboxylic acid(4282-31-9)Related Product Information

• OXALIC ACID
• Dibenzothiophene
• Thiophene
• 2,5-PYRIDINEDICARBOXYLIC ACID
• EPA
• Cephalothin sodium
• Tetrahydrothiophene
• Thifensulfuron
• Thiophene-3-ethanol
• 2-Thiophenecarboxylic acid
• Thiophene-2,3-dicarboxylicacid
• Ascoric Acid
• 2-Thiophenecarboxaldehyde
• THIOPHEN-3-YLMETHYL-AMMONIUM CHLORIDE
• COPPER(I) THIOPHENE-2-CARBOXYLATE
• Thiophene-2,5-dicarbonitrile
• 2-Thiopheneacetic acid
• THIENO[3,2-B]PYRIDINE