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LIMAPROST

Basic information Safety Supplier Related

LIMAPROST Basic information

Product Name:
LIMAPROST
Synonyms:
  • (2e,11-alpha,13e,15s,17s)-11,15-dihydroxy-17,20-dimethyl-9-oxoprost-2,13-die
  • ,13e,15s,17s)-
  • 11α,15s-dihydroxy-17s,20-dimethyl-9-oxo-prosta-2e,13e-dien-1-oic acid
  • 17S,20-Dimethyl-trans-D2-PGE1
  • 2-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl]-, (2E)- (9CI)
  • Prosta-2,13-dien-1-oic acid, 11,15-dihydroxy-17,20-dimethyl-9-oxo-, (2E,11a,13E,15S,17S)-
  • 17α,20-dimethyl-δ2-PGE1, 11α,15S-Dihydroxy-17S,20-dimethyl-9-oxo-prosta-2E,13E-dien-1-oic acid
  • (2E)-7-[(1R)-2β-[(1E,3S,5S)-3-Hydroxy-5-methyl-1-nonenyl]-3α-hydroxy-5-oxocyclopentan-1α-yl]-2-heptenoic acid
CAS:
74397-12-9
MF:
C22H36O5
MW:
380.52
Product Categories:
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
74397-12-9.mol
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LIMAPROST Chemical Properties

Melting point:
97-100°
Boiling point:
550.6±50.0 °C(Predicted)
Density 
1.118
storage temp. 
-20°C
solubility 
DMF: soluble
form 
crystalline
pka
4.78±0.10(Predicted)
color 
White to off-white
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Safety Information

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
36/37/39-45
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
UK8362500

MSDS

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LIMAPROST Usage And Synthesis

Uses

Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal.

Definition

ChEBI: Limaprost is a long-chain fatty acid.

Biochem/physiol Actions

Limaprost exhibits cytoprotective, vasodilatory, and antiplatelet activity. Limaprost has the potential to treat lumbar spinal canal stenosis (LSCS) and several ischaemic symptoms of thromboangiitis obliterans (TAO).

LIMAPROSTSupplier

Wuhan Wsem Biological Co., Ltd. Gold
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027-83778876 13667159345
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Shanghai Boyle Chemical Co., Ltd.
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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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Chemvon Biotechnology Co., Ltd
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021-50790412
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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