Isobutyl acetoacetate Chemical Properties

Melting point:

177-179 °C(Solv: ethyl ether (60-29-7))

Boiling point:

100 °C/22 mmHg (lit.)

Density 

0.98 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.424(lit.)

FEMA 

2177 | ISOBUTYL ACETOACETATE

Flash point:

173 °F

storage temp. 

Sealed in dry,Store in freezer, under -20°C

pka

10?+-.0.46(Predicted)

form 

liquid

color 

clear

Odor

at 10.00 % in dipropylene glycol. sweet wine brandy fruity

Odor Type

fruity

JECFA Number

597

BRN 

1761405

LogP

1.60

CAS DataBase Reference

7779-75-1(CAS DataBase Reference)

NIST Chemistry Reference

Butanoic acid, 3-oxo-, 2-methylpropyl ester(7779-75-1)

EPA Substance Registry System

Butanoic acid, 3-oxo-, 2-methylpropyl ester (7779-75-1)

Safety Information

WGK Germany 

3

HS Code 

2918.30.9000

MSDS

• Language:English Provider:SigmaAldrich

Isobutyl acetoacetate Usage And Synthesis

Description

Isobutyl acetoacetate has a sweet, winey, brandy-like odor and a sweet and slightly fruity flavor. May be prepared from isobutyl acetate by heating in the presence of sodium isobutylate.

Chemical Properties

Isobutyl acetoacetate has a sweet, winy, brandy-like odor and a sweet and slightly fruity flavor.

Chemical Properties

Clear liquid

Uses

Isobutyl acetoacetate is used as intermediate for the production of pharmaceuticals (e.g. Nisoldipine). Product Data Sheet

Uses

Isobutyl Acetoacetate is a building block that has been used as a reactant in the preparation of b-annulated 1,4-dihydropyridine derivatives as TGFβ signaling inhibitors.

Definition

ChEBI: 2-Methylpropyl 3-oxobutanoate is an oxo carboxylic acid.

Preparation

From isobutyl acetate by heating in the presence of sodium isobutylate.

Isobutyl acetoacetate(7779-75-1)Related Product Information

• isobutyl oleate
• Ethyl acetoacetate
• Diisobutyl phthalate
• Butyl acrylate resin
• Acetyl tributyl citrate
• Butyl stearate
• Tris(trimethylsilyl)phosphate
• tert-Butyl bromoacetate
• TITANIUM ISOBUTOXIDE
• Triisobutyl phosphate
• Acetoacetic Acid
• tert-Butyl chloroacetate
• Butyric Acid
• Tributyl citrate
• Butyl acetate
• Dimethyl succinate
• DL-sec-Butyl acetate
• Phenylacetic acid isobutyl ester