Prosaikogenin F
Prosaikogenin F Basic information
- Product Name:
- Prosaikogenin F
- Synonyms:
-
- Prosaikogenin F
- Prosapogenin F
- VQBQVYADHPXLAM-LLYXJXEPSA-N
- (13,28-Epoxy-16β,23-dihydroxy-5α-olean-11-en-3β-yl)6-deoxy-β-D-galactopyranoside
- 3-O-β-D-fucopyranosylsaikogenin F
- inhibit,Prosaikogenin F,monoglycoside,Inhibitor,hemolytic,corticosterone,anticancer
- β-D-Galactopyranoside, (3β,4α,16β)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-
- Prosaikogenin F, 10 mM in DMSO
- CAS:
- 99365-20-5
- MF:
- C36H58O8
- MW:
- 618.84092
- Mol File:
- 99365-20-5.mol
Prosaikogenin F Chemical Properties
- Melting point:
- 246-250 °C
- Boiling point:
- 722.4±60.0 °C(Predicted)
- Density
- 1.26±0.1 g/cm3(Predicted)
- pka
- 13.04±0.70(Predicted)
- form
- Solid
- color
- White to off-white
- Stability:
- Hygroscopic
Prosaikogenin F Usage And Synthesis
Uses
Prosaikogenin F is a monoglycoside with anticancer and hemolytic properties[1][2].
in vivo
In mice, intraperitoneal administration of Saikosaponin A and its intestinal metabolite, Prosaikogenin F, show corticosterone secretion-inducing activity at a dose of 0.1 mmol/kg, and maximally increase it at a dose of 0.4 mmol/kg[3].
References
[1] Lu Shi, et al. A Potential Anti-cancer Compound Separated from the Chloroform Extract of the Chinese Medicine Formula Shenqi San. Curr Med Sci. 2020 Feb;40(1):138-144. DOI:10.1007/s11596-020-2157-5
[2] M Nose, S Amagaya, et al. Effects of saikosaponin metabolites on the hemolysis of red blood cells and their adsorbability on the cell membrane. Chem Pharm Bull (Tokyo). 1989 Dec;37(12):3306-10. DOI:10.1248/cpb.37.3306
[3] M Nose, et al. Corticosterone secretion-inducing activity of saikosaponin metabolites formed in the alimentary tract. Chem Pharm Bull (Tokyo). 1989 Oct;37(10):2736-40. DOI:10.1248/cpb.37.2736
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Prosaikogenin F(99365-20-5)Related Product Information
- [16α,23,28-Trihydroxy-5α-oleana-11,13(18)-dien-3β-yl]6-deoxy-β-D-galactopyranoside
- kuwanon G
- Prosaikogenin H
- brusatol
- 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxy-2-methoxyphenyl)-8-[5-methyl-2-(1-methylvinyl)-4-hexenyl]-4H-1-benzopyran-4-one
- prosaikogenin A
- Prosaikogenin G
- Saikosaponin C
- Saikosaponin a
- Saikosaponin B2
- Saikosaponin F
- Saikosaponin B1
- Saikosaponin D
- saikosaponin e
- [16β,28-Dihydroxy-11,12,13,18-tetradehydrooleanan-3β-yl]4-O-(6-deoxy-α-L-mannopyranosyl)-6-O-(β-D-glucopyranosyl)-β-D-glucopyranoside
- 11(α)-methoxysaikosaponin F
- SAIKOGENIN D