Basic information Safety Supplier Related

Prosaikogenin F

Basic information Safety Supplier Related

Prosaikogenin F Basic information

Product Name:
Prosaikogenin F
Synonyms:
  • Prosaikogenin F
  • Prosapogenin F
  • VQBQVYADHPXLAM-LLYXJXEPSA-N
  • (13,28-Epoxy-16β,23-dihydroxy-5α-olean-11-en-3β-yl)6-deoxy-β-D-galactopyranoside
  • 3-O-β-D-fucopyranosylsaikogenin F
  • inhibit,Prosaikogenin F,monoglycoside,Inhibitor,hemolytic,corticosterone,anticancer
  • β-D-Galactopyranoside, (3β,4α,16β)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-
  • Prosaikogenin F, 10 mM in DMSO
CAS:
99365-20-5
MF:
C36H58O8
MW:
618.84092
Mol File:
99365-20-5.mol
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Prosaikogenin F Chemical Properties

Melting point:
246-250 °C
Boiling point:
722.4±60.0 °C(Predicted)
Density 
1.26±0.1 g/cm3(Predicted)
pka
13.04±0.70(Predicted)
form 
Solid
color 
White to off-white
Stability:
Hygroscopic
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Prosaikogenin F Usage And Synthesis

Uses

Prosaikogenin F is a monoglycoside with anticancer and hemolytic properties[1][2].

in vivo

In mice, intraperitoneal administration of Saikosaponin A and its intestinal metabolite, Prosaikogenin F, show corticosterone secretion-inducing activity at a dose of 0.1 mmol/kg, and maximally increase it at a dose of 0.4 mmol/kg[3].

References

[1] Lu Shi, et al. A Potential Anti-cancer Compound Separated from the Chloroform Extract of the Chinese Medicine Formula Shenqi San. Curr Med Sci. 2020 Feb;40(1):138-144. DOI:10.1007/s11596-020-2157-5
[2] M Nose, S Amagaya, et al. Effects of saikosaponin metabolites on the hemolysis of red blood cells and their adsorbability on the cell membrane. Chem Pharm Bull (Tokyo). 1989 Dec;37(12):3306-10. DOI:10.1248/cpb.37.3306
[3] M Nose, et al. Corticosterone secretion-inducing activity of saikosaponin metabolites formed in the alimentary tract. Chem Pharm Bull (Tokyo). 1989 Oct;37(10):2736-40. DOI:10.1248/cpb.37.2736

Prosaikogenin FSupplier

ShangHai YuanYe Biotechnology Co., Ltd.
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Shanghai Hekang Biotechnology Co., Ltd.
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JinJin Le Chemical Co., Ltd
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