Iopromide Chemical Properties

Melting point:

broad (160?C transition)

Boiling point:

840.9±65.0 °C(Predicted)

Density 

2.173±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,2-8°C

solubility 

Freely soluble in water and in dimethyl sulfoxide, practically insoluble in ethanol (96 per cent) and in acetone.

pka

10.62±0.70(Predicted)

Stability:

Hygroscopic

CAS DataBase Reference

73334-07-3(CAS DataBase Reference)

EPA Substance Registry System

1,3-Benzenedicarboxamide, N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-N1-methyl- (73334-07-3)

Safety Information

Hazard Codes 

N

Risk Statements 

50/53

Safety Statements 

60-61

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

3

RTECS 

CZ2230000

HS Code 

2924296000

Toxicity

LD50 in mice, rats (g iodine/kg body weight): 16.5, 11.4 i.v. (Muetzel)

Iopromide Usage And Synthesis

Description

Iopromide is a non-ionic, water-soluble X-ray contrast agent for intravascular administration. Iopromide can cause acute kidney injury and is used in animal models of contrast-induced nephropathy.

Chemical Properties

White Solid

Uses

Contrast molecule

Uses

Labelled Iopromide. Nonionic, injectable radio-contrast medium. Diagnostic aid (radiopaque medium).

Definition

ChEBI: A dicarboxylic acid diamide that consists of N-methylisophthalamide bearing three iodo substituents at positions 2, 4 and 6, a methoxyacetyl substituent at position 5 and two 2,3-dihydroxypropyl groups attached to the amide nitrogens. A ater soluble x-ray contrast agent for intravascular administration.

brand name

Ultravist (Berlex).

General Description

Iopromide is a low-osmolar,nonionic monomer with 48% bound iodine content. It is indicatedfor use in angiography, excretory urography, andnumerous CT procedures.

Iopromide(73334-07-3)Related Product Information

• Iohexol
• Ioversol
• N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide
• Formamide
• Iodine
• Iopromide
• 3-(N-BENZYL-N-METHYLAMINO)-1,2-PROPANEDIOL
• 5-Amino-N,N'-bis(2,3-dihydroxypropyl)isophthalamide
• 5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide
• 5-Amino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide
• 3,5-DIMETHYL-4-IODOANILINE
• 3-AMINOMETHYL-N,N-DIMETHYL-BENZAMIDE
• 3-DIMETHYLAMINOMETHYL-BENZYLAMINE
• 4-Iodo-N,N-dimethylbenzamide
• 5-AMINO-ISOPHTHALAMIDE
• IOPROMIDE RELATED COMPOUND A (50 MG) (5- AMINO-N,N'-BIS(2,3-DIHYDROXYPROPYL)-2,4,6-TRIIO- DO-N-METHYL-1,3-BENZENEDICARBOXAMIDE)
• IOPROMIDE RELATED COMPOUND A (50 MG) (5-AMINO-N,N'-BIS(2,3-DIHYDROXYPROPYL)-2,4,6-TRIIO-DO-N-METHYL-1,3-BENZENEDICARBOXAMIDE)
• 2,4-DIIODO-3,5-DIMETHYLANILINE