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5-Bromothiophene-2-sulfonamide

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5-Bromothiophene-2-sulfonamide Basic information

Product Name:
5-Bromothiophene-2-sulfonamide
Synonyms:
  • 5-BROMOTHIOPHENE-2-SULFONAMIDE
  • 5-BROMO-THIOPHENE-2-SULFONIC ACID AMIDE
  • 5-BROMOTHIOPHENE-2-SULPHONAMIDE
  • 2-BROMO THIOPHENE-5-SULFONAMIDE
  • 2-THIOPHENESULFONAMIDE, 5-BROMO-
  • BUTTPARK 21\07-10
  • 5-Bromo-2-thiophenesulfonamide
  • 5-BROMOTHIOPHENE-2-SULFONYLAMINE
CAS:
53595-65-6
MF:
C4H4BrNO2S2
MW:
242.11
Product Categories:
  • Heterocycle-oher series
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Thiophenes
  • ThiophenesBuilding Blocks
  • Fluorobenzene
  • Thiophene&Benzothiophene
  • Thiophene intermediates
  • Building Blocks
  • C4 to C6
  • Chemical Synthesis
  • Halogenated Heterocycles
Mol File:
53595-65-6.mol
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5-Bromothiophene-2-sulfonamide Chemical Properties

Melting point:
138-142 °C (lit.)
Boiling point:
386.4±52.0 °C(Predicted)
Density 
1.951±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
9.75±0.60(Predicted)
color 
Light orange to Yellow to Green
CAS DataBase Reference
53595-65-6(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
HS Code 
29350090

MSDS

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5-Bromothiophene-2-sulfonamide Usage And Synthesis

Chemical Properties

White to light yellow crystal powder

Uses

5-Bromothiophene-2-sulfonamide may be used to synthesize:

  • 5-(phenylthio)thiophene-2-sulfonamide
  • 5-bromothiophene-2-sulfonyl acetamide
  • 5-arylthiophene-2-sulfonylacetamide derivatives

It may also be used in the preparation of the following 5-arylthiophene-2-sulfonamides:
  • 5-phenylthiophene-2-sulfonamide
  • 5-(3-cyno-5-(trifluoromethyl)phenyl)thiophene-2-sulfonamide
  • 5-(3,5-bis(trifluoromethyl)phenyl)thiophene-2-sulfonamide
  • 5′-chloro-2,2′-bithiophene-5-sulfonamide
  • 5′-methyl-2,2′-bithiophene-5-sulfonamide
  • 5-p-tolylthiophene-2-sulfonamide
  • 5-(4-methoxyphenyl)thiophene-2-sulfonamide
  • 5-(4-chlorophenyl)thiophene-2-sulfonamide
  • 5-(3,4-dichlorophenyl)thiophene-2-sulfonamide
  • 5-(3,5-dimethylphenyl)thiophene-2-sulfonamide
  • 5-(4-chloro-3-fluorophenyl)thiophene-2-sulfonamide

General Description

5-Bromothiophene-2-sulfonamide can be synthesized by reacting 5-bromothiophene-2-sulfonyl fluoride with ammonium hydroxide in 2-methyltetrahydrofuran.

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