N-CAPROYL-L-HOMOSERINE LACTONE Chemical Properties

Melting point:

101-106 °C

Boiling point:

434.0±34.0 °C(Predicted)

Density 

1.08±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 10 mg/ml

form 

A crystalline solid

pka

15.03±0.20(Predicted)

color 

White to off-white

BRN 

1640340

Safety Information

Safety Statements 

24/25

WGK Germany 

3

F 

3-10

MSDS

• Language:English Provider:SigmaAldrich

N-CAPROYL-L-HOMOSERINE LACTONE Usage And Synthesis

Uses

Induces violacein expression in a Chromobacterium violaceum mutant usually not able to produce homoserine lactones.

Definition

ChEBI: N-(2-Oxooxolan-3-yl)hexanamide is a N-acyl-amino acid.

Biochem/physiol Actions

N-Hexanoyl-DL-homoserine lactone is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella and are involved in quorum sensing, cell to cell communication among bacteria. Some AHLs are potent chemoattractants for human immune cells such as neutrophils.

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