α-Bromo-2,3,4,5,6-pentafluorotoluene Chemical Properties

Melting point:

19-20 °C(lit.)

Boiling point:

174-175 °C(lit.)

Density 

1.728 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.471(lit.)

Flash point:

181 °F

storage temp. 

Store below +30°C.

solubility 

Chloroform (Soluble), Ethyl Acetate (Slightly), Methanol (Slightly)

form 

Liquid

Specific Gravity

1.728

color 

Clear colorless to yellow

Water Solubility 

Hydrolyzes in water.

Sensitive 

Lachrymatory

BRN 

647808

CAS DataBase Reference

1765-40-8(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, (bromomethyl)pentafluoro-(1765-40-8)

Safety Information

Hazard Codes 

C,Xi

Risk Statements 

34-36/37/38-36/37-22

Safety Statements 

26-36/37/39-45-23-27

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

F 

19

Hazard Note 

Irritant/Lachrymatory

HazardClass 

8

PackingGroup 

II

HS Code 

29039990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

α-Bromo-2,3,4,5,6-pentafluorotoluene Usage And Synthesis

Chemical Properties

CLEAR COLOURLESS TO YELLOWISH LIQUID

Uses

Pentafluorobenzyl bromide (PFB-Br) is an alkylating reagent which can be used to modify hydroxyl groups, carboxyl groups, sulfhydryl groups, and amines.PFB-Br can also be used to measure nitrite and peroxynitrite.It is a versatile reagent.

Uses

2,3,4,5,6-Pentafluorobenzyl bromide is used as a reagent for derivatization of alcohols, carboxylic acids, sulfonamides for GC and polyfunctional thiols. It is used for the preparation of pentafluorobenzyl esters of organic acids for determination by capillary and GC. It is also used to derivatize N-7-substituted guanine adducts of DNA for determination by GC-electron capture-MS.

Uses

Learn more in the Product Information

Definition

ChEBI: Pentafluorobenzyl bromide is a member of the class benzyl bromides that is benzyl bromide in which the hydrogens at positions 2, 3, 4, 5 and 6 of the phenyl ring are replaced by fluoro groups. It is a versatile derivatization agent in chromatography and mass spectrometry. It is a member of benzyl bromides and a member of fluorobenzenes.

General Description

Pentafluorobenzyl bromide (PFB-Br) is a derivatization reagent. Excess reagent may be removed by reaction with an aminophenol. It is an alkylation reagent suitable for electron capture detector (ECD) detection. It is also a lachrymator.

α-Bromo-2,3,4,5,6-pentafluorotoluene(1765-40-8)Related Product Information

• PENTAFLUOROPHENYLHYDRAZINE
• PENTAFLUOROPHENYL TRIFLUOROACETATE
• Isopropoxypentafluorobenzene
• Pentafluorobenzyl chloride
• METHYL PENTAFLUOROBENZOATE
• IODOPENTAFLUOROBENZENE
• PENTAFLUORONITROBENZENE
• 2,3,4,5,6-Pentafluorobenzyl alcohol
• 2,3,4,5,6-Pentafluoroaniline
• 2,3,4,5,6-PENTAFLUOROPHENYLACETONITRILE
• Pentafluorobenzonitrile
• Pentafluorobenzoyl chloride
• Pentafluorobenzaldehyde
• 2,3,4,5,6-PENTAFLUOROBENZENEBORONIC ACID
• Chloropentafluorobenzene
• 2,3,6-TRIFLUOROBENZYL BROMIDE
• 3-Fluorobenzyl bromide
• Benzyl bromide