Basic information Safety Supplier Related

HL 725

Basic information Safety Supplier Related

HL 725 Basic information

Product Name:
HL 725
Synonyms:
  • 4,6-trimethylphenyl)imino)--2-((monohydrochloride
  • 4h-pyrimido(6,1-a)isoquinolin-4-one,2,3,6,7-tetrahydro-9,10-dimethoxy-3-methyl
  • HL 725
  • HL 725 HCL
  • Trequinsin, Hydrochloride - CAS 78416-81-6 - Calbiochem
  • 2,3,6,7-TETRAHYDRO-9,10-DIMETHOXY-3-METHYL-2-[(2,4,6-TRIMETHYLPHENYL)IMINO]-4H-PYRIMIDO[6,1-A]ISOQUINOLIN-4-ONE HYDROCHLORIDE
  • 9,10-DIMETHOXY-2-MESITYLIMINO-3-METHYL-2,3,6,7-TETRAHYDRO-4H-PYRIMIDO-(6,1-A)-ISOQUINOLIN-4-ONE, HCL
  • 9,10-DIMETHOXY-2-MESITYLIMINO-3-METHYL-2,3,6,7-TETRAHYDRO-4H-PYRIMIDO-[6,1A]-ISOQUINOLIN-4-ONE HYDROCHLORIDE
CAS:
78416-81-6
MF:
C24H28ClN3O3
MW:
441.95
Mol File:
78416-81-6.mol
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HL 725 Chemical Properties

Melting point:
210-211 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
storage temp. 
Desiccate at RT
solubility 
DMSO: 100 mM; Ethanol: 100 mM
form 
Pale yellow solid
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Safety Information

WGK Germany 
3
RTECS 
UW7727000

MSDS

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HL 725 Usage And Synthesis

Uses

Trequinsin Hydrochloride is an ultrapotent inhibitor of phosphodiesterase (PDE) 3.

Uses

PDE inhibitor

Biological Activity

Extremely potent inhibitor of cGMP-inhibited phosphodiesterase (PDE3; IC 50 = 250 pM). Potently inhibits arachidonic acid-induced aggregation of human platelets (IC 50 = 50 pM). Orally active antihypertensive agent; reduces systemic blood pressure in both normotensive and hypertensive animal models.

storage

Desiccate at RT

HL 725Supplier

3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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3bsc@sina.com
Shanghai TaoSu Biochemical Technology Co., Ltd.
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021-33632979
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EMMX Biotechnology LLC
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888-539-0666
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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Shanghai Rechem science Co., Ltd.
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21-31433387 15618786686
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sales@rechemscience.com