PAM3-CYS-SER-SER-ASN-ALA-OH
PAM3-CYS-SER-SER-ASN-ALA-OH Basic information
- Product Name:
- PAM3-CYS-SER-SER-ASN-ALA-OH
- Synonyms:
-
- 2,3-bis(palmitoyloxy)-2-propyl-n-palmitoyl-cysteinyl-seryl-seryl-asparaginyl-al
- anine
- 2,3-bis(palmitoyloxy)-2-propyl-N-palmitoyl-cysteinyl-seryl-seryl-asparaginyl-alanine
- PALMITOYL-CYS ((RS)-2,3-DI(PALMITOYLOXY)-PROPYL)-SER-SER-ASN-ALA-OH
- PAM3-CYS-SER-SER-ASN-ALA-OH
- MITOGENIC PENTAPEPTIDE
- S-[2,3-BIS(PALMITOYLOXY)-(2RS)-PROPYL]-N-PALMITOYL-(R)-CYS-SER-SER-ASN-ALA-OH
- PaM3Cys-Ser-Ser-Asn-Ala-OH, PaM3CSSNA
- CAS:
- 87173-03-3
- MF:
- C67H124N6O14S
- MW:
- 1269.8
- Mol File:
- 87173-03-3.mol
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PAM3-CYS-SER-SER-ASN-ALA-OH Chemical Properties
- Boiling point:
- 1304.2±65.0 °C(Predicted)
- Density
- 1.078±0.06 g/cm3(Predicted)
- storage temp.
- -15°C
- pka
- 3.36±0.10(Predicted)
- Sequence
- {Palmitoyl}-{Cys((RS)-2,3-di(palmitoyloxy)-propyl)}-Ser-Ser-Asn-Ala
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PAM3-CYS-SER-SER-ASN-ALA-OH Usage And Synthesis
Uses
Mitogenic Pentapeptide (Tripalmitoyl pentapeptide) is an effective activator of B lymphocyte mitogen and polyclonal. Mitogen Pentapeptide is a synthetic N-terminal analog of E. coli outer membrane lipoproteins (cysteinyl-seryl-seryl-asparaginyl-alanine). Mitogenic Pentapeptide can be used for the study of immune adjuvants[1][2].
References
[1] Bessler WG, et al. Synthetic lipopeptide analogs of bacterial lipoprotein are potent polyclonal activators for murine B lymphocytes. J Immunol. 1985 Sep;135(3):1900-5. PMID:3874908
[2] Lex A, et al. A synthetic analogue of Escherichia coli lipoprotein, tripalmitoyl pentapeptide, constitutes a potent immune adjuvant. J Immunol. 1986 Oct 15;137(8):2676-81. PMID:3531339
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