2-(Methylsulfinyl)pyridine Chemical Properties

Melting point:

6 °C

Boiling point:

95-96 °C(Press: 1.5 Torr)

Density 

1.28±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

pka

-0.15±0.10(Predicted)

Appearance

Colorless to light yellow Liquid

Safety Information

Risk Statements 

22-34

Safety Statements 

26-36/37/39-35

HS Code 

29333990

2-(Methylsulfinyl)pyridine Usage And Synthesis

Chemical Properties

Yellow oily liquid

Synthesis

General procedure for the synthesis of 2-(methylsulfinyl)pyridine and 2-(methylsulfonyl)pyridine from 2-methylthiopyridine: 2-methylthiopyridine (130.3 mg, 1.0 mmol), 35% H2O2 aqueous solution (247.7 mg, 2.5 mmol), and Ti-IEZ-MWW catalyst (9.9 mg) were added to the test tube fitted with a magnetic stirrer. ). The reaction mixture was stirred at 50°C for 3 hours. The reaction process was analyzed by GC through a toluene solution with biphenyl as internal standard to determine the conversion and yield. The results showed >99% yield of 2-(methylsulfonyl)pyridine, >99% conversion of 2-methylthiopyridine and >99% selectivity (yield/conversion).

References

[1] Tetrahedron, 2014, vol. 70, # 41, p. 7584 - 7592
[2] Synlett, 2015, vol. 26, # 18, p. 2547 - 2552
[3] Tetrahedron, 2014, vol. 70, # 41, p. 7584 - 7592

2-(Methylsulfinyl)pyridine(21948-75-4)Related Product Information

• 2-PYRIDINESULFONYLACETONITRILE
• 2-(PYRIDIN-2-YLSULFONYL)ETHANETHIOAMIDE
• 2-HYDROXYIMINO-2-(2-PYRIDYLSULFONYL)ACETONITRILE
• 5-[3-CHLORO-5-(TRIFLUOROMETHYL)PYRID-2-YLSULPHONYL]THIOPHENE-2-SULPHONYL CHLORIDE
• 2-[(2-CHLOROETHYL)SULFONYL]-5-(TRIFLUOROMETHYL)PYRIDINE
• 1-(2-[(2-PYRIDYLSULFONYL)METHYL]-1,3-THIAZOL-4-YL)ETHAN-1-ONE
• METHYL 2-[[5-(TRIFLUOROMETHYL)-2-PYRIDYL]SULFONYL]ACETATE
• 2-([5-(TRIFLUOROMETHYL)-2-PYRIDYL]SULFONYL)ETHYL 2,3,3-TRICHLOROACRYLATE
• 6-(BUTYLSULFONYL)-N-(4-CHLOROPHENYL)NICOTINAMIDE
• 2,6-BIS[(4-CHLOROPHENYL)SULFONYL]-3-CYANO-4-METHYLPYRIDINIUM-1-OLATE
• O1-(2-CHLOROACETYL)-2-(2-PYRIDYLSULFONYL)ETHANEHYDROXIMAMIDE
• 2-[(4-METHYLPHENYL)SULFONYL]-5-NITROPYRIDINIUM-1-OLATE
• 6-(SEC-BUTYLSULFONYL)-N-(4-CHLOROPHENYL)NICOTINAMIDE
• N1-(2-BROMOETHYL)-2-METHYL-2-([5-(TRIFLUOROMETHYL)-2-PYRIDYL]SULFONYL)PROPANAMIDE
• 5-(CHLOROMETHYL)-3-[(2-PYRIDYLSULFONYL)METHYL]-1,2,4-OXADIAZOLE
• 2-[(4-CHLOROPHENYL)SULFONYL]-5-NITROPYRIDINIUM-1-OLATE
• N-(4-CHLOROPHENYL)-6-(PROPYLSULFONYL)NICOTINAMIDE
• N-(2,4-DIFLUOROPHENYL)-6-(ISOPROPYLSULFONYL)NICOTINAMIDE