6-AZA-2'-DEOXYURIDINE
6-AZA-2'-DEOXYURIDINE Basic information
- Product Name:
- 6-AZA-2'-DEOXYURIDINE
- Synonyms:
-
- 2'-Deoxy-6-azauridine
- 2-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazine-3,5-dione
- 1,2,4-Triazine-3,5(2H,4H)-dione, 2-(2-deoxy-β-D-erythro-pentofuranosyl)-
- 2-(2-Deoxy-β-D-erythro -pentofuranosyl)-1,2,4- triazine-3,5(2H ,4H )-dione
- 6-Aza-2'-deoxyuridine
- 2’-Deoxy-6-azauridine
- CAS:
- 20500-29-2
- MF:
- C8H11N3O5
- MW:
- 229.19
- Mol File:
- 20500-29-2.mol
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6-AZA-2'-DEOXYURIDINE Chemical Properties
- Melting point:
- 182 °C(Solv: ethanol (64-17-5))
- Density
- 1.90±0.1 g/cm3(Predicted)
- pka
- 7.88±0.20(Predicted)
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6-AZA-2'-DEOXYURIDINE Usage And Synthesis
Uses
6-Aza-2'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
6-AZA-2'-DEOXYURIDINESupplier
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