4,6-DICHLORO-5-NITRO-2-PROPYLTHIOPYRIMIDINE Chemical Properties

Boiling point:

377.8±37.0 °C(Predicted)

Density 

1.54±0.1 g/cm3(Predicted)

vapor pressure 

0.005Pa at 25℃

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Sparingly), DMSO (Sparingly), Ethyl Acetate (Slightly)

pka

-8.48±0.50(Predicted)

form 

Oil

color 

Colourless to Dark Yellow

Stability:

Unstable in DMSO Solution

InChI

InChI=1S/C7H7Cl2N3O2S/c1-2-3-15-7-10-5(8)4(12(13)14)6(9)11-7/h2-3H2,1H3

InChIKey

DDEDQHVHVPJFAC-UHFFFAOYSA-N

SMILES

C1(SCCC)=NC(Cl)=C([N+]([O-])=O)C(Cl)=N1

LogP

2.6 at 25℃ and pH7.3

Surface tension

70.5-71.7mN/m at 9.1mg/L and 25℃

Safety Information

HS Code 

2933599590

4,6-DICHLORO-5-NITRO-2-PROPYLTHIOPYRIMIDINE Usage And Synthesis

Chemical Properties

4,6-Dichloro-5-nitro-2-propylthiopyrimidine is colorless or yellow oil liquid at room temperature and pressure, solubility in dichloromethane, chloroform, dimethyl sulfoxide, ethyl acetate is general, and insoluble in water, and dissolved in dimethyl sulfoxide is easy to deteriorate.

Uses

4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine is used as a reactnat in the synthesis of carba-nucleosides as potent antagonists of ADP purinergic receptor P2Y12 on human platelets.

4,6-DICHLORO-5-NITRO-2-PROPYLTHIOPYRIMIDINE(145783-14-8)Related Product Information

• TICAGRELOR
• Canagliflozin
• Ticagrelor Sulfone
• Tetrahydro-2,2-dimethyl-4,7-methano-6H-1,3-dioxolo[4,5-d][1,2]oxazine-6-carboxylic acid phenylmethyl ester
• 2-((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yloxy)ethanol L-tataric acid
• 4,6-dichloro-2-propylthiopyrimidine-5-amine
• (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol
• (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate
• 1-Acetyladamantane Intermediate
• (1R trans)-2-(3,4-difluorophenyl)cyclopropane amine. HCl
• Ethanol, 2-[[(3aR,4S,6R,6aS)-6-[[5-aMino-6-chloro-2-(propylthio)-4-pyriMidinyl]aMino]tetrahydro-2,2-diMethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-
• ethyCyclopropanamine, 2-(3,4-difluorophenyl)-, (1R,2S)- (REACH)
• (1R,2R)-2-(3,4-difluorophenyl)cyclopropane carboxaMide
• (1R trans)-2-(3,4-difluorophenyl)cyclopropane amine
• CarbaMicacid,N-[(3aS,4R,6S,6aR)-tetrahydro-6-hydroxy-2,2-diMethyl-4H-cyclopenta-1,3-dioxol-4-yl]-,phenylMethyl ester
• Cyclopropanamine,2-(3,4-difluorophenyl)-(1R,2S) -(2R,3R)-2,3-dihydroxybutanedioate (1:1)
• 2-(((3aR,4S,6R,6aS)-6-(7-aMino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-2,2-diMethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol
• (3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)aMino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-2,2-