2-CHLORO-4-TRIFLUOROMETHOXYBENZENEBORONIC ACID Chemical Properties

Melting point:

150-152 °C

Boiling point:

294.1±50.0 °C(Predicted)

Density 

1.53±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,2-8°C

pka

8.00±0.58(Predicted)

Safety Information

HS Code 

2931900090

2-CHLORO-4-TRIFLUOROMETHOXYBENZENEBORONIC ACID Usage And Synthesis

Uses

(2-Chloro-4-trifluoromethoxyphenyl)boronic Acid is an intermediate used to prepare aza- and diazabiphenyl analogs of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine. It is also used in the synthesis of aryl(alkylamino)nitropyridines via amination of chlorohydroxynitropyridine with aliphatic amines followed by chlorination, and Suzuki-coupling with arylboronic acids.

2-CHLORO-4-TRIFLUOROMETHOXYBENZENEBORONIC ACID(345226-20-2)Related Product Information

• 4-Trifluoromethoxyphenylboronic acid
• Boronic acid, [4-(difluoromethoxy)phenyl]- (9CI)
• 2-CHLORO-4-HYDROXYPHENYLBORONIC ACID
• 2-Chloro-4-methoxyphenylboronic acid
• 2-CHLORO-4-TRIFLUOROMETHOXYBENZENEBORONIC ACID