ChemicalBook > Product Catalog > Pharmaceutical intermediates > Bulk Drug Intermediates > 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-
1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-
1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- Basic information
- Product Name:
- 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-
- Synonyms:
-
- 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-
- (S)-2-((2-oxo-3-(4-(3-oxoMorpholino)phenyl)oxazolidin-5-yl)Methyl)isoindoline-1,3-dione
- 2-({(5S)-2-oxo-3-[4-(3-oxoMorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}Methyl)-1H-isoindole-1,3(2H)-dione
- RivaroxabanInterMediates-01
- 4-[4-[(5S)-5-PhthaliMidoMethyl-2-oxo-3-oxazolidinyl]phenyl]-3-Morpholinone
- 2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1,3(2H)-dione
- Rivaroxaban Intermediate5
- Rivaroxaban Phthalimido Impurity
- CAS:
- 446292-08-6
- MF:
- C22H19N3O6
- MW:
- 421.4
- EINECS:
- 610-201-0
- Product Categories:
-
- Chiral Reagents
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Intermediate of Rivaroxaban
- Mol File:
- 446292-08-6.mol
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1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- Chemical Properties
- Melting point:
- 213-215°C
- Boiling point:
- 702.9±55.0 °C(Predicted)
- Density
- 1.465±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- pka
- 0.99±0.20(Predicted)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- 12mg/L at 20℃
- LogP
- -0.2 at 25℃
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1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- Usage And Synthesis
Uses
1H-isoindole-1,3(2H)-dione, 2-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]- is an important intermediate for the synthesis of rivaroxaban, which is an anticoagulant and the first orally active direct factor Xa inhibitor.
Chemical Properties
White Solid
Uses
Rivaroxaban intermediate.
Flammability and Explosibility
Non flammable
1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-Supplier
Suzhou lipin Chemical Co., Ltd Gold
- Tel
- 0512-0512-67509664 19888480046
Harway Pharma CO., LTD Gold
- Tel
- 0546-5612566 13793982289
- lucy@harwaypharma.com
Jiangxi taisinor Co., Ltd. Gold
- Tel
- 13576915071
- taisinor@vip.163.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
BeiJing Hwrk Chemicals Limted
- Tel
- 0757-86329057 18934348241
- sales4.gd@hwrkchemical.com
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1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-(446292-08-6)Related Product Information
- Rivaroxaban Metabolite 8
- AcetaMide, N-[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]-
- 2-ThiophenecarboxaMide, N-[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]-
- 5-R-Rivaroxaban
- Rivaroxaban
- POLYSTYRENE IODOSOACETATE
- 1,2-Cyclohexanedione
- (S)-(+)-Epichlorohydrin
- 4-(4-NITROPHENYL)MORPHOLIN-3-ONE
- (S)-(+)-Glycidyl Phthalimide
- 4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one
- (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one.HCl
- 5-CHLOROTHIOPHENE-2-CARBONYL CHLORIDE
- Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
- 3-MORPHOLINONE, 4-[4-[(5S)-5-(AMINOMETHYL)-2-OXO-3-OXAZOLIDINYL]PHENYL]-
- 4-(4-AMINOPHENYL)MORPHOLIN-3-ONE
- 5-Chloro-2-thiophenecarboxylic Acid
- m-(Trifluoromethyl)phenylacetic acid