ChemicalBook > Product Catalog > Organic Chemistry > Hydrocarbons and derivatives > 5-(Hydroxymethyl)-alpha,alpha,alpha',alpha'-tetramethyl-1,3-benzenediacetonitrile
5-(Hydroxymethyl)-alpha,alpha,alpha',alpha'-tetramethyl-1,3-benzenediacetonitrile
5-(Hydroxymethyl)-alpha,alpha,alpha',alpha'-tetramethyl-1,3-benzenediacetonitrile Basic information
- Product Name:
- 5-(Hydroxymethyl)-alpha,alpha,alpha',alpha'-tetramethyl-1,3-benzenediacetonitrile
- Synonyms:
-
- 2-[3-(1-Cyano-1-methylethyl)-5-(hydroxymethyl)phenyl]-2-methylpropanenitrile
- 5-(Hydroxymethyl)-alpha,alpha,alpha',alpha'-tetramethyl-1,3-benzenediacetonitrile
- 2-[3-(1-Cyano-1-Methylethyl)-5-(hydroxyMethyl)phenyl]-2-
- 1,3-Benzenediacetonitrile, 5-(hydroxyMethyl)-α1,α1,α3,α3-tetraMethyl-
- Anastrozole EP Impurity E
- 2,2'-[5-(Hydroxymethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
- 2,2'-[5-(hydroxymethyl)benzene-1,3- diyl]bis(2-methylpropanenitrile)
- Anastrozole Impurity 10（EP Impurity E）
- CAS:
- 120511-88-8
- MF:
- C15H18N2O
- MW:
- 242.32
- Mol File:
- 120511-88-8.mol
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5-(Hydroxymethyl)-alpha,alpha,alpha',alpha'-tetramethyl-1,3-benzenediacetonitrile Chemical Properties
- Melting point:
- 150-160℃
- Boiling point:
- 382.3±37.0 °C(Predicted)
- Density
- 1.084
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 14.34±0.10(Predicted)
- color
- White to Off-White
- InChI
- InChI=1S/C15H18N2O/c1-14(2,9-16)12-5-11(8-18)6-13(7-12)15(3,4)10-17/h5-7,18H,8H2,1-4H3
- InChIKey
- PLEAQICJSGOGID-UHFFFAOYSA-N
- SMILES
- C1(C(C)(C)C#N)=CC(CO)=CC(C(C)(C)C#N)=C1
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5-(Hydroxymethyl)-alpha,alpha,alpha',alpha'-tetramethyl-1,3-benzenediacetonitrile Usage And Synthesis
Uses
2-[3-(Cyanodimethylmethyl)-5-hydroxymethylphenyl]-2-methylpropionitrile (Anastrozole EP Impurity E ) is an impurity of Anastrozole (A637425), an aromatase inhibitor which functions as an antineoplastic (1,2). Anastrozole is used in post-menopausal women with advanced breast cancer.
Definition
ChEBI: 2-[3-(2-cyanopropan-2-yl)-5-(hydroxymethyl)phenyl]-2-methylpropanenitrile is an alkylbenzene.
5-(Hydroxymethyl)-alpha,alpha,alpha',alpha'-tetramethyl-1,3-benzenediacetonitrileSupplier
BOC Sciences
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BOC Sciences
- Tel
- 16314854226
- info@bocsci.com
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5-(Hydroxymethyl)-alpha,alpha,alpha',alpha'-tetramethyl-1,3-benzenediacetonitrile(120511-88-8)Related Product Information
- Anastrozole IMpurity (3-(1-Cyano-1-Methylethyl)-alfa,alfa-diMethyl-5-(1H-,1,2,4-triazole-1-ylMethyl)-benzeneacetaMide)
- p-Toluenesulfonic acid monohydrate
- Anastrozole
- Anastrozole IMpurity (3-(1-Cyano-1-Methylethyl)-alfa,alfa-diMethyl-5-(1H-,1,2,4-triazole-1-ylMethyl)-benzeneacetic acid)
- 5-Methyl-1,3-benzenediacetonitrile
- Anastrozole IMpurity (alfa1 , alfa1, alfa3, alfa3-TetraMethyl-5-(1H-1,2,4-triazol-1-ylMethyl)-1,3-BenzenediacetaMide)
- α,α,α’,α’-Tetramethyl-5-(dibromomethyl)-1,3-benzenediacetonitrile
- 3,5-Bis(2-cyanoprop-2-yl)toluene
- Di-Destriazole Anastrozole DiMer IMpurity
- 3,5-Bis(bromomethyl)toluene
- Anastrozole Impurity 11
- 2-[3-CHLOROMETHYL-5-(CYANO-DIMETHYL-METHYL)-PHENYL]-2-METHYL-PROPIONITRILE
- 2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni
- Anastrozole N-glucuronide
- Anastrozole iMpurity
- Anastrozole IMpurity (alfa1 , alfa1, alfa3, alfa3-TetraMethyl-5-(1H-1,2,4-triazol-1-ylMethyl)-1,3-Benzenediacetic acid)
- α-Desmethyl Anastrozole
- 3,5-Bis(2-cyanoprop-2-yl)benzyl bromide