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Doravirine

Basic information Safety Supplier Related

Doravirine Basic information

Product Name:
Doravirine
Synonyms:
  • MK-1439
  • 3-chloro-5-((1-((4-Methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)Methyl)-2-oxo-4-(trifluoroMethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile
  • 3-Chloro-5-[[1-[(4,5-dihydro-4-methyl-5-oxo-1H-1,2,4-triazol-3-yl)methyl]-1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]benzonitrile
  • Doravirine / MK-1439
  • Doravirine
  • MK-1439(Doravirine)
  • Benzonitrile, 3-chloro-5-[[1-[(4,5-dihydro-4-methyl-5-oxo-1H-1,2,4-triazol-3-yl)methyl]-1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]-
  • 3-chloro-5-[1-[(4-methyl-5-oxo-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)pyridin-3-yl]oxybenzonitrile
CAS:
1338225-97-0
MF:
C17H11ClF3N5O3
MW:
425.75
Mol File:
1338225-97-0.mol
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Doravirine Chemical Properties

Melting point:
>278°C (dec.)
Density 
1.56±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly, Heated), Methanol (Slightly, Heated)
form 
Solid
pka
8.04±0.20(Predicted)
color 
White to Off-White
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Doravirine Usage And Synthesis

Uses

Doravirine is a novel non-nucleoside inhibitor of HIV-1 reverse transcriptase with potent activity against wild-type virus.

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