Antidesmone
Antidesmone Basic information
- Product Name:
- Antidesmone
- Synonyms:
-
- Antidesmone
- (5S)-1,5,6,7-Tetrahydro-3-methoxy-2-methyl-5-octyl-4,8-quinolinedione
- 4,8-Quinolinedione, 1,5,6,7-tetrahydro-3-methoxy-2-methyl-5-octyl-, (5S)-
- (5S)-3-methoxy-2-methyl-5-octyl-1,5,6,7-tetrahydroquinoline-4,8-dione
- (s)-3-methoxy-2-methyl-5-octyl-1,5,6,7-tetrahydroquinoline-4,8-dione
- CAS:
- 222629-77-8
- MF:
- C19H29NO3
- MW:
- 319.44
- Mol File:
- 222629-77-8.mol
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Antidesmone Chemical Properties
- Boiling point:
- 468.3±45.0 °C(Predicted)
- Density
- 1.07±0.1 g/cm3(Predicted)
- storage temp.
- Store at 0-8 °C
- pka
- -4.58±0.70(Predicted)
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Antidesmone Usage And Synthesis
Uses
Antidesmone is a isoquinoline alkaloid that can be isolated from Antidesma membranaceum[1]. Antidesmone can prevent acute lung injury in vivo via inhibiting MAPK and NF-κb activities[2].
References
[1] Lu X, et al. Antidesmone, a unique tetrahydroquinoline alkaloid, prevents acute lung injury via regulating MAPK and NF-κB activities. Int Immunopharmacol. 2017 Apr;45:34-42. DOI:10.1016/j.intimp.2017.01.026
[2] Buske, et al. Antidesmone, a novel type isoquinoline alkaloid from Antidesma membranaceum (Euphorbiaceae). Tetrahedron, 55(4), 1079–1086.
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