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Isodunnial

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Isodunnial Basic information

Product Name:
Isodunnial
Synonyms:
  • Isodunnial
  • Isodunnianol
  • [1,1'-Biphenyl]-2,2'-diol, 5,5'-di-2-propen-1-yl-3-[4-(2-propen-1-yl)phenoxy]-
  • sodunnianol
CAS:
139726-30-0
MF:
C27H26O3
MW:
398.49
Mol File:
139726-30-0.mol
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Isodunnial Chemical Properties

Boiling point:
511.2±50.0 °C(Predicted)
Density 
1.121±0.06 g/cm3(Predicted)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
9.00±0.50(Predicted)
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Isodunnial Usage And Synthesis

Uses

Isodunnianol is a autophagy inducer. Isodunnianol induces autophagy and increases he expression of pAMPK172, pULK1555,decreases teh expression of pULK1757, SQSTM2. Isodunnianol decreases Doxorubicin.html" class="link-product" target="_blank">Doxorubicin (HY-15142A)-induced cardiotoxicity[1].

target

NF-kB | NOS | ROS

References

[1] Chen C , et al . Isodunnianol alleviates duxorubicin-induced myocardial injury by activating protective autophagy. Food Funct. 2019 May 22;10(5):2651-2657. DOI:10.1039/c9fo00063a

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