Vasicil
Vasicil Basic information
- Product Name:
- Vasicil
- Synonyms:
-
- Vasicil
- (+)-6-Hydroxypeganine
- 6-Hydroxypeganine
- 6-Hydroxyvasicine
- Pyrrolo(2,1-b)quinazoline-3,7-diol, 1,2,3,9-tetrahydro-, (R)-
- Pyrrolo[2,1-b]quinazoline-3,7-diol, 1,2,3,9-tetrahydro-, (3S)-
- CAS:
- 5081-51-6
- MF:
- C11H12N2O2
- MW:
- 204.23
- Product Categories:
-
- Alkaloids
- Mol File:
- 5081-51-6.mol
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Vasicil Chemical Properties
- Melting point:
- 260 °C
- Boiling point:
- 465.0±55.0 °C(Predicted)
- Density
- 1.52±0.1 g/cm3(Predicted)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 7.89±0.40(Predicted)
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Vasicil Usage And Synthesis
Uses
Vasicinol is a reversible inhibitor of sucrase (IC50: 250 μM). Vasicinol is a HbF inducer. Vasicinol also inhibits Angiotensin-converting Enzyme (ACE). Vasicinol is apyrroquinazoline alkaloid that can be isolated from Adhatoda vasica[1][2].
Definition
ChEBI: Vasicinol is a member of quinazolines.
References
[1] Gao H, et al. Inhibitory effect on α-glucosidase by Adhatoda vasica Nees. Food Chem. 2008 Jun 1;108(3):965-72. DOI:10.1016/j.foodchem.2007.12.002
[2] Tehreem S, et al. A UPLC-DAD-Based Bio-Screening Assay for the Evaluation of the Angiotensin Converting Enzyme Inhibitory Potential of Plant Extracts and Compounds: Pyrroquinazoline Alkaloids from Adhatoda vasica as a Case Study. Molecules. 2021 Nov 18;26(22):6971. DOI:10.3390/molecules26226971
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