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4-(4-Bromo-2-fluoroanilino)-7-hydroxy-6-methoxyquinazoline

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4-(4-Bromo-2-fluoroanilino)-7-hydroxy-6-methoxyquinazoline Basic information

Product Name:
4-(4-Bromo-2-fluoroanilino)-7-hydroxy-6-methoxyquinazoline
Synonyms:
  • 6-Methoxy-7-hydroxy-4-(2''-fluoro-4''-broMoaniline)quinazoline
  • 4-(4-bromo-2-fluorophenylamino)-6-methoxyquinazolin-7-ol
  • 4-(4-Bromo-2-fluoroanilino)-7-hydroxy-6-methoxyquinazoline
  • 4-[(4-Bromo-2-fluorophenyl)amino]-6-methoxy-7-Quinazolinol
  • 7-Quinazolinol, 4-[(4-broMo-2-fluorophenyl)aMino]-6-Methoxy-
  • 4-(4-bromo-2-fluoroanilino)-6-methoxy-1H-quinazolin-7-one
  • 4-(4-Bromo-2-fluoroanilino)-7-hydroxy-6-methoxyquinazoline ISO 9001:2015 REACH
CAS:
196603-96-0
MF:
C15H11BrFN3O2
MW:
364.17
EINECS:
688-137-8
Mol File:
196603-96-0.mol
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4-(4-Bromo-2-fluoroanilino)-7-hydroxy-6-methoxyquinazoline Chemical Properties

Melting point:
268-270 °C
Boiling point:
471.0±45.0 °C(Predicted)
Density 
1.663
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
5.51±0.40(Predicted)
color 
White to Off-White
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4-(4-Bromo-2-fluoroanilino)-7-hydroxy-6-methoxyquinazoline Usage And Synthesis

Uses

4-(4-Bromo-2-fluoroanilino)-7-hydroxy-6-methoxyquinazolin is used in the synthesis of [18F]-(R)-FEPAQ, a potential PET imaging agent for VEGFR2. This would be helpful in the imaging of VEGFR in cance r patients.

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