Ethyl 4-cyanobenzoate Chemical Properties

Melting point:

52-54 °C (lit.)

Boiling point:

140°C/11mmHg(lit.)

Density 

1.1999 (rough estimate)

refractive index 

1.5060 (estimate)

Flash point:

>230 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

soluble in Methanol

form 

powder to crystal

color 

White to Almost white

λmax

263nm(lit.)

CAS DataBase Reference

7153-22-2(CAS DataBase Reference)

NIST Chemistry Reference

Ethyl 4-cyanobenzoate(7153-22-2)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-36-36/37/39

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29269090

MSDS

• Language:English Provider:Ethyl 4-cyanobenzoate
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

Ethyl 4-cyanobenzoate Usage And Synthesis

Chemical Properties

white to light yellow crystalline powder

Synthesis

General procedure for the synthesis of ethyl 4-cyanobenzoate from ethanol and 4-cyanobenzaldehyde: 4-cyanobenzaldehyde (25 mmol), [bmim]N3 (75 mmol) and ethanol (75 mmol) were thoroughly mixed and the reaction was stirred at 50-60 °C. The reaction process was monitored by thin layer chromatography (TLC) using ethyl acetate/petroleum ether (1:7) as eluent. After completion of the reaction, the target product ethyl 4-cyanobenzoate was isolated by preparative chromatography using ethyl acetate/petroleum ether as eluent.

References

[1] Synthesis, 2010, # 2, p. 276 - 282
[2] Comptes Rendus Chimie, 2012, vol. 15, # 11-12, p. 1077 - 1080
[3] Bulletin of the Korean Chemical Society, 2011, vol. 32, # 6, p. 2070 - 2072
[4] Journal of Organometallic Chemistry, 2018, vol. 857, p. 123 - 137

Ethyl 4-cyanobenzoate(7153-22-2)Related Product Information

• Ethyl acetate
• Ethylparaben
• Ethylbenzene
• Ethyl propionate
• Ethyl 2-chloromethylbenzoate
• ETHYL 2-CYANOACRYLATE
• Ethyl benzoate
• Ethyl vanillin
• Ethanol
• Ethyl 4-hydroxybenzoate,sodium salt
• Ethyl acrylate
• Ethyl formate
• ETHYL ANTHRANILATE
• Methylene dithiocyanate
• 4-(Hydroxymethyl)phenoxyacetic acid
• Sodium methylparaben
• Methyl 4-cyanobenzoate
• Sodium propylparaben