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Methyl 5-chloro-6-methylpyrazine-2-carboxylate

Basic information Pharmaceutical intermediate Safety Supplier Related

Methyl 5-chloro-6-methylpyrazine-2-carboxylate Basic information

Product Name:
Methyl 5-chloro-6-methylpyrazine-2-carboxylate
Synonyms:
  • 5-Chloro-6-methyl-2-pyrazinecarboxylic acid methyl ester
  • Methyl 5-chloro-6-methylpyrazine-2-carboxylate
  • 5-Chloro-6-methyl-pyrazine-2-carboxylic acid methyl ester
  • N-1H-BENZIMIDAZOL-4-YLFORMAMIDE
  • 2-Pyrazinecarboxylic acid, 5-chloro-6-methyl-, methyl ester
  • Methyl 5-chloro-6-methylpyrazine-2-carboxylate ISO 9001:2015 REACH
  • 1,4-Butanediamine,N1,N4-bis(7-chloro-5-quinolinyl)-
CAS:
77168-85-5
MF:
C7H7ClN2O2
MW:
186.6
Mol File:
77168-85-5.mol
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Methyl 5-chloro-6-methylpyrazine-2-carboxylate Chemical Properties

Melting point:
40-43℃
Boiling point:
260℃
Density 
1.314
Flash point:
111℃
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
powder
pka
-3.86±0.10(Predicted)
color 
Yellow
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Safety Information

HS Code 
2933199090
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Methyl 5-chloro-6-methylpyrazine-2-carboxylate Usage And Synthesis

Pharmaceutical intermediate

The N-methyl-d-aspartate (NMDA) receptor is arguably an important signaling mechanism in the human brain and NMDA receptors play a critical role in regulating the strength of synapses, that is, in regulating synaptic plasticity. Methyl 5-chloro-6-methylpyrazine-2-carboxylate is the key materials to prepare the NMDA receptor.

Uses

Methyl 5-?Chloro-?6-?methylpyrazine-?2-?carboxylate is a reactant used in the synthesis of 4,5-dihydro-5-oxo-2-pyrazinecarboxylic acid 1-oxides.

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