1,5,15-Tri-O-MethylMorindol
1,5,15-Tri-O-MethylMorindol Basic information
- Product Name:
- 1,5,15-Tri-O-MethylMorindol
- Synonyms:
-
- 1,5,15-Tri-O-MethylMorindol
- 2-Hydroxy-1,5-dimethoxy-6-(methoxymethyl)-9,10-anthracenedione
- methylmorindol1,5,15-Tri-O-
- 2-hydroxy-1,5-dimethoxy-6-(methoxymethyl)anthracene-9,10-dione
- 15-Tri-O-methylmorindol
- 9,10-Anthracenedione, 2-hydroxy-1,5-dimethoxy-6-(methoxymethyl)-
- CAS:
- 942609-65-6
- MF:
- C18H16O6
- MW:
- 328.32
- Mol File:
- 942609-65-6.mol
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1,5,15-Tri-O-MethylMorindol Chemical Properties
- Melting point:
- 186-190 °C
- Boiling point:
- 546.5±50.0 °C(Predicted)
- Density
- 1.341±0.06 g/cm3(Predicted)
- pka
- 6.90±0.20(Predicted)
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1,5,15-Tri-O-MethylMorindol Usage And Synthesis
Uses
1,5,15-Trimethylmorindol is an anthraquinone isolated from the leaves of Morinda citrifolia. 1,5,15- trimethylmorindol (25 μg/mL) does not show significant cytotoxic activity on the human T-cell leukemia cell line, Jurkat, by itself but it shows cytotoxicity (IC50 14.5-15.0 μg/mL) when combined with 0.5-1.5 μg/mL of TRAIL in the cell proliferation assay[1].
References
[1] Junko Takashima, et al. New constituents from the leaves of Morinda citrifolia. Chem Pharm Bull (Tokyo). 2007 Feb;55(2):343-5. DOI:10.1248/cpb.55.343
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