Octahydro-1H-indole-2-carboxylic acid Chemical Properties

Melting point:

233-234 °C (decomp)(Solv: 1,4-dioxane (123-91-1); water (7732-18-5))

Boiling point:

318.6±25.0 °C(Predicted)

Density 

1.135±0.06 g/cm3(Predicted)

storage temp. 

-15°C

solubility 

Methanol (Slightly), Water (Slightly)

form 

Solid

pka

2.47±0.20(Predicted)

color 

White to Off-White

InChI

InChI=1/C9H15NO2/c11-9(12)8-5-6-3-1-2-4-7(6)10-8/h6-8,10H,1-5H2,(H,11,12)/t6-,7-,8-/s3

InChIKey

CQYBNXGHMBNGCG-VTCOHLDGNA-N

SMILES

N1[C@@]2([H])[C@]([H])(CCCC2)C[C@@H]1C(O)=O |&1:1,3,10,r|

CAS DataBase Reference

80828-13-3(CAS DataBase Reference)

Octahydro-1H-indole-2-carboxylic acid Usage And Synthesis

Chemical Properties

White Crystalline Solid

Uses

(2R,3aR,7aR)-rel-OctahydroIndole-2-carboxylic Acid is a reactant in the preparation of Perindoprilat (P287530), an angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.

Uses

Trandolapril intermediate

Octahydro-1H-indole-2-carboxylic acid(80828-13-3)Related Product Information

• cis-Octahydro-isoindole
• Indometacin
• Ethyl 2-(Chlorosulfonyl)acetate
• Indole-3-butyric acid
• Indole-3-acetic acid
• Indole-2-carboxylic acid
• Folic acid
• Perindoprilat
• Trandolapril
• Indolapril
• Perindopril erbumine
• BOC-OIC-OH
• Trandolaprilat
• FMOC-OIC-OH
• L-Octahydroindole-2-carboxylic acid
• (R)OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID
• (2S,3aR,7aS)-1H-Octahydroindole-2-carboxylic acid hydrochloride
• Perindopril