Hedragonic acid Chemical Properties

Boiling point:

548.8±50.0 °C(Predicted)

Density 

1.10±0.1 g/cm3(Predicted)

pka

4.65±0.70(Predicted)

Hedragonic acid Usage And Synthesis

Uses

Hedragonic acid is an oleane-type triterpenoid compound, which can be isolated from the stems and roots of the southern snake vine. Hedragonic acid is a ligand and agonist for FXR. Hedragonic acid protected mice from liver damage caused by acetaminophen overdose and reduced liver inflammation[1].

References

[1] Lu Y, et al. Identification of an Oleanane-Type Triterpene Hedragonic Acid as a Novel Farnesoid X Receptor Ligand with Liver Protective Effects and Anti-inflammatory Activity. Mol Pharmacol. 2018 Feb;93(2):63-72. DOI:10.1124/mol.117.109900