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ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Bulk Drug Intermediates >  N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester

N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester

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N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Basic information

Product Name:
N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester
Synonyms:
  • 1. (S)-isopropyl2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)
  • N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester (SIDE CHAIN)
  • L-Alanine, N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-methylethyl ester
  • propan-2-yl (2S)-2-{[(S)-pentafluorophenoxy(phenoxy)phosphoryl]amino}propanoate
  • Sofosbuvir side chain N-1
  • Sofosbuvir Intermediate 5
  • isopropyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate
  • N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester
CAS:
1334513-02-8
MF:
C18H17F5NO5P
MW:
453.3
EINECS:
695-076-0
Product Categories:
  • Sofosbuvir intermediate
  • Pharmaceuticalintermediates
Mol File:
1334513-02-8.mol
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N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Chemical Properties

Melting point:
133-135°C
Boiling point:
442.6±55.0 °C(Predicted)
Density 
1.405
vapor pressure 
0Pa at 25℃
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
-3.81±0.70(Predicted)
form 
Solid
color 
White
LogP
4.1 at 30℃ and pH7.37
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Safety Information

HS Code 
2931599090
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N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Usage And Synthesis

Uses

N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester is a reactant in the synthesis of phosphoramidate imidazo[2,1-f][1,2,4]triazine-4-amine adenosine prodrugs that can increase anti-HCV activity.

N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl esterSupplier

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