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Cefpirome sulfate

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Cefpirome sulfate Basic information

Product Name:
Cefpirome sulfate
Synonyms:
  • 1-[[(6r,7r)-7-[[(2z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-6,7-dihydro-5h-cyclopenta[b]pyridinium sulfate
  • CEFPIROME SULFATE
  • Keitin)
  • Cefquinome base
  • CefpiromeSulfate3%
  • 1-(((6R,7R)-7-((Z)-2-(2-AMinothiazol-4-yl)-2-(MethoxyiMino)acetaMido)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)Methyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-1-iuM hydrogensulfate
  • CEFPIROME SULFATE USP 27
  • (6r-rboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-
CAS:
98753-19-6
MF:
C22H24N6O9S3
MW:
612.66
EINECS:
685-392-7
Product Categories:
  • api
  • Pharmaceutical intermediate
  • cephalosporins antibiotics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Pharmaceutical raw material
  • Antibacterial
  • Miscellaneous
  • 98753-19-6
Mol File:
98753-19-6.mol
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Cefpirome sulfate Chemical Properties

Melting point:
198-2020C (dec)
alpha 
25D -4.7° (c = 5 in H2O)
RTECS 
UW8970000
storage temp. 
Inert atmosphere,2-8°C
solubility 
Soluble in DMSO
form 
Solid
color 
White to Off-White
λmax
265nm(Buffer)(lit.)
Merck 
14,1940
CAS DataBase Reference
98753-19-6(CAS DataBase Reference)
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Safety Information

HS Code 
2941.90.3000
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Cefpirome sulfate Usage And Synthesis

Description

Cefpirome sulfate is a new injectable cephalosporin indicated for the treatment of severe urinary and respiratory tract infections, including septicemia and nosocomial infections. Cefpirome sulfate is reported to be the first true fourth-generation cephalosporin due to its similar activities to third-generation antibiotics against Gram-positive bacteria and to first-generation antibiotics against Gram-negative bacteria. Its efficacy against P.aeruginosa is comparable to ceftazidime. The broad spectrum of activity includes Klebsiella, methicillin-sensitive staphylococci, penicillin-resistant pneumococci, E.coli which generates extended-spectrum beta-lactamases and multi-resistant organisms such as Citrobacter, Enterobacter and Serratia.

Chemical Properties

White Crystalline Powder

Originator

Hoechst AG (Germany)

Uses

A fourth generation cephalosporin antibiotic

Definition

ChEBI: Cefpirome sulfate is an azaheterocycle sulfate salt. It is functionally related to a cefpirome.

brand name

Cefrom (Hoechst-Roussel).

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