SQ 109
SQ 109 Basic information
- Product Name:
- SQ 109
- Synonyms:
-
- SQ 109
- NSC 722041
- N-[(2E)-3,7-Dimethyl-2,6-octadienyl]-N'-tricyclo[3.3.1.1(3,7)]dec-2-yl-1,2-ethanediamine
- Cenobamate
- N'-(2-adamantyl)-N-[(2E)-3,7-dimethylocta-2,6-dienyl]ethane-1,2-diamine
- SQ 109; SQ-109; NSC 722041
- 1,2-Ethanediamine, N1-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-N2-tricyclo[3.3.1.13,7]dec-2-yl-
- SQ109 >=98% (HPLC)
- CAS:
- 502487-67-4
- MF:
- C22H38N2
- MW:
- 330.55
- Mol File:
- 502487-67-4.mol
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SQ 109 Chemical Properties
- Boiling point:
- 450.0±33.0 °C(Predicted)
- Density
- 0.97±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly)
- form
- oil
- pka
- 9.80±0.20(Predicted)
- color
- colorless to yellow
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SQ 109 Usage And Synthesis
Uses
SQ109 has been used:
- as an antitubercular?agent to study its interactions with mycobacterial membrane proteins large 3 (MmpL3) binding pocket
- as a positive control to determine the minimum inhibitory concentration (MIC) of ohmyungsamycins (OMS) A and B against Mycobacterium tuberculosis?(Mtb) using the resazurin microtiter assay (REMA) plate method
- as an inhibitor of MmpL3 to explore the utility of mycobacterial CRISPR interference for validating target gene essentiality and compound mode of action
General Description
SQ109 is a 1,2-ethylenediamine, which is related to ethambutol.
Biochem/physiol Actions
SQ109 exhibits activity against Helicobacter pylori and the fungi Candida albicans. It might also possess anti-bacterial activity.
target
Mycobacterium
SQ 109Supplier
ChemShuttle, Inc.
- Tel
- 0510-83588313-802 18800520310;
- sales@chemshuttle.com
Haoyuan Chemexpress Co., Ltd.
- Tel
- 021-58950125
- info@chemexpress.com
MedChemexpress LLC
- Tel
- 021-58955995
- sales@medchemexpress.cn
ShangHai Caerulum Pharma Discovery Co., Ltd.
- Tel
- 18149758185 18149758185
- sales-cpd@caerulumpharma.com
AdooQ Bioscience CHINA
- Tel
- 025-58849295 18951903616;
- info@adooq.cn