DO2A Chemical Properties

Boiling point:

526.4±50.0 °C(Predicted)

Density 

1.146±0.06 g/cm3(Predicted)

solubility 

Aqueous Acid (Slightly), DMSO (Very Slightly, Heated, Sonicated), Water (Slightly)

pka

4.22±0.10(Predicted)

form 

Solid

color 

White to Off-White

Stability:

Hygroscopic

DO2A Usage And Synthesis

Description

DO2A is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DO2A can be used for conjugation of peptides and radionuclides.

Uses

1,4,7,10-Tetraazacyclododecane-1,7-diacetic Acid is a macrocyclic ligand and is an impurity of Gadoteridol (G125900), which is used as an MRI contrast chelating agent.

DO2A(112193-75-6)Related Product Information

• DO3A
• DOTA
• 1,4,7,10-TETRAAZACYCLODODECANE-1,4,7,10-TETRAYL-TETRAKIS(METHYLPHOSPHONIC ACID)
• DOTMA(M-160)
• p-NO2-Bn-DOTA(B-199)
• 1,4,8,11-TETRAAZACYCLOTETRADECANE-1,4,8,11-TETRAACETIC ACID TETRAHYDROCHLORIDE HYDRATE