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2,4,6-TRIFLUOROBENZYL AMINE

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2,4,6-TRIFLUOROBENZYL AMINE Basic information

Product Name:
2,4,6-TRIFLUOROBENZYL AMINE
Synonyms:
  • RARECHEM AL BW 0429
  • 2,4,6-TRIFLUOROBENZYL AMINE
  • Benzenemethanamine, 2,4,6-trifluoro- (9CI)
  • 1-(2,4,6-Trifluorophenyl)methylamine
  • 2,4,6-trifluorobenzylaminine
  • (2,4,6-Trifluorophenyl)methylamine
  • Benzenemethanamine, 2,4,6-trifluoro-
  • Chlorfenvinphos Impurity 7
CAS:
214759-21-4
MF:
C7H6F3N
MW:
161.12
Product Categories:
  • Fluorine series
  • HALIDE
  • 214759-21-4
Mol File:
214759-21-4.mol
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2,4,6-TRIFLUOROBENZYL AMINE Chemical Properties

Boiling point:
165℃
Density 
1.320
Flash point:
63℃
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
8.16±0.10(Predicted)
form 
liquid
color 
Colourless
Water Solubility 
Slightly Soluble in water (1.2 g/L) (25°C).
Sensitive 
Air Sensitive
Stability:
Air Sensitive
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Safety Information

Hazard Codes 
Xi,C
Risk Statements 
34
Safety Statements 
20-26-36/37/39-45
RIDADR 
UN2735
Hazard Note 
Irritant
HazardClass 
8
PackingGroup 
III
HS Code 
2921490090
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2,4,6-TRIFLUOROBENZYL AMINE Usage And Synthesis

Uses

Used to prepare dyes. Industrially used in natural gas and refinery process streams. They also are used in polymer industry as monomers. Amines find use as additives for lubricating oils, engine fuels, and asphalt, and are producers of ethanolamines.

Uses

2,4,6-Trifluorobenzylamine can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

Put into 50 gram 2 into 1000ml autoclave, 4,6- trifluorobenzonitriles, 2.5 grams of raney-ni, 75 gram 25% of ammonia, 500 grams of methanol, control temperature to be 90 DEG C, and mixing speed is 350r/min, are passed through hydrogen hydrogenation, hydrogenation pressure 1mpa, logical hydrogen time 8 Hour reaction terminates, filtering catalyst raney-ni, the methanol in distillation gained filtrate, and distillation terminates addition dichloromethane extraction Take, extract elder generation normal pressure concentrated solvent, then vacuum distillation product, obtain 43.6 grams of product, 2,4,6- trifluoromethyl benzonitrile amine contents 99%, yield is calculated as 85% with 2,4,6- trifluorobenzonitriles.

2,4,6-TRIFLUOROBENZYL AMINESupplier

Shanghai Rochi Pharmaceutical Co., Ltd. Gold
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