Exalamide
Exalamide Basic information
- Product Name:
- Exalamide
- Synonyms:
-
- 2-(hexyloxy)-benzamid
- 2-n-hexyloxybenzamide
- h.p.216
- o-hexyloxy-benzamid
- HBA
- HYPERAN
- EXALAMIDE
- HBA, Hyperan, 2-(Hexyloxy)benzamide
- CAS:
- 53370-90-4
- MF:
- C13H19NO2
- MW:
- 221.3
- EINECS:
- 258-504-3
- Product Categories:
-
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Steroids
- Amines
- Aromatics
- Mol File:
- 53370-90-4.mol
Exalamide Chemical Properties
- Melting point:
- 72-74°C
- Boiling point:
- 362.36°C (rough estimate)
- Density
- 1.0451 (rough estimate)
- refractive index
- 1.5175 (estimate)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 15.62±0.50(Predicted)
- color
- White
Exalamide Usage And Synthesis
Chemical Properties
White Solid
Originator
Hyperan,S.S. Pharm,Japan,1980
Uses
Exalamide is used as an antifungal (topical). Exalamide is a derivative of salicylamide.
Definition
ChEBI: An arenecarboxamide that is salicylamide in which the phenolic hydroxy group has been converted to the corresponding hexyl ether. It has been used as a topical antifungal agent.
Manufacturing Process
4.6 g sodium were dissolved in 150 ml ethanol and 27.4 g (0.2 mol) salicylamide added. The solution was refluxed gently and 24.6 g (0.2mol) nhexyl- bromide added gradually. The mixture was refluxed for six hours, the precipitated sodium bromide filtered off, and most of the alcohol removed by distillation. Water was then added to the residue, and the 2-nhexyloxybenzamide filtered off. It crystallized from 50% aqueous ethanol in colorless crystals, MP 71°C.
Therapeutic Function
Antifungal
ExalamideSupplier
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- 010-82848833 400-666-7788
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- inquiries@lgmpharma.com
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- 021-50135380
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- Tel
- 010-56205725
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Exalamide(53370-90-4)Related Product Information
- Boc-D-Glutamine
- Formamide
- Acrylamide
- Benzenesulfonamide
- Sulfanilamide
- Polyacrylamide
- PHTHALAMIDE
- Nicotinamide
- Chlorantraniliprole
- Polyamide
- Ethopabate
- Benzamide
- N,N-Dimethylformamide
- NAPHTHOL AS NONANOATE
- Otilonium bromide
- NAPHTHOL AS-BI BETA-D-GLUCURONIDE
- EXALAMIDE
- NAPHTHOL AS-BI BETA-D-GALACTOPYRANOSIDE