Dodoviscin I Chemical Properties

Boiling point:

664.4±55.0 °C(Predicted)

Density 

1.43±0.1 g/cm3(Predicted)

pka

6.33±0.40(Predicted)

Dodoviscin I Usage And Synthesis

Uses

Dodoviscin I (Dodoviscin A) is an adipogenic agent that increases triglyceride content in 3T3L1 mouse fibroblasts. Dodoviscin I inhibits ERK2 with an IC50 of 10.79 μM.

References

[1] Yang R, et al. Identification of potential extracellular signal-regulated protein kinase 2 inhibitors based on multiple virtual screening strategies. Front Pharmacol. 2022 Nov 18;13:1077550. DOI:10.3389/fphar.2022.1077550
[2] Zhang LB, et al. Isoprenylated flavonoid and adipogenesis-promoting constituents of Dodonaea viscosa. J Nat Prod. 2012 Apr 27;75(4):699-706. DOI:10.1021/np2009797

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