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Irinotecan Hydroxyl Acid

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Irinotecan Hydroxyl Acid Basic information

Product Name:
Irinotecan Hydroxyl Acid
Synonyms:
  • Irinotecan IMpurity
  • Irinotecan Impurity 28
  • Indolizino[1,2-b]quinoline-7-acetic acid, α,12-diethyl-9,11-dihydro-α,2-dihydroxy-8-(hydroxymethyl)-9-oxo-, (αS)-
  • (S)-2-(12-ethyl-2-hydroxy-8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl)-2-hydroxybutanoic acid, sodium salt (1:2)
  • Irinotecan Hydroxyl Acid
CAS:
142677-15-4
MF:
C22H22N2O6
MW:
410.43
Mol File:
142677-15-4.mol
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Irinotecan Hydroxyl Acid Chemical Properties

Boiling point:
829.8±65.0 °C(Predicted)
Density 
1.54±0.1 g/cm3(Predicted)
solubility 
DMSO (Slightly, Heated), Methanol (Slightly, Sonicated), Water (Slightly)
form 
Solid
pka
2.88±0.10(Predicted)
color 
Light Yellow to Dark Yellow
Stability:
Hygroscopic
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Irinotecan Hydroxyl Acid Usage And Synthesis

Uses

The active metabolite of Irinotecan (carboxylate form). SN-38 lactone and carboxylate may be considered pharmacokinetically distinct agents.

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